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Solution conformation of the (-)-trans-anti-benzo[c]phenanthrene-dA ([BPh]dA) adduct opposite dT in a DNA duplex: intercalation of the covalently attached benzo[c]phenanthrenyl ring to the 3'-side of the adduct site and comparison with the (+)-trans-anti-[BPh]dA opposite dT stereoisomer.
Cosman M, Laryea A, Fiala R, Hingerty BE, Amin S, Geacintov NE, Broyde S, Patel DJ. Cosman M, et al. Among authors: broyde s. Biochemistry. 1995 Jan 31;34(4):1295-307. doi: 10.1021/bi00004a024. Biochemistry. 1995. PMID: 7827077
Solution conformation of the (+)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the major groove.
Cosman M, Fiala R, Hingerty BE, Amin S, Geacintov NE, Broyde S, Patel DJ. Cosman M, et al. Among authors: broyde s. Biochemistry. 1994 Sep 27;33(38):11507-17. doi: 10.1021/bi00204a013. Biochemistry. 1994. PMID: 7918364
Solution conformation of the (+)-cis-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove.
Cosman M, Fiala R, Hingerty BE, Amin S, Geacintov NE, Broyde S, Patel DJ. Cosman M, et al. Among authors: broyde s. Biochemistry. 1994 Sep 27;33(38):11518-27. doi: 10.1021/bi00204a014. Biochemistry. 1994. PMID: 7918365
E., Luna, E., Harvey, R. G., Geacintov, N. E., Broyde, S., & Patel, D. J. (1993) Biochemistry 32, 4145-4155]. This is not surprising since the dC opposite the lesion site was looped out of the helix and it can be readily replaced by a deletion site through minor …
E., Luna, E., Harvey, R. G., Geacintov, N. E., Broyde, S., & Patel, D. J. (1993) Biochemistry 32, 4145-4155]. This is not …
Solution conformation of the (+)-trans-anti-[BPh]dA adduct opposite dT in a DNA duplex: intercalation of the covalently attached benzo[c]phenanthrene to the 5'-side of the adduct site without disruption of the modified base pair.
Cosman M, Fiala R, Hingerty BE, Laryea A, Lee H, Harvey RG, Amin S, Geacintov NE, Broyde S, Patel D. Cosman M, et al. Among authors: broyde s. Biochemistry. 1993 Nov 23;32(46):12488-97. doi: 10.1021/bi00097a029. Biochemistry. 1993. PMID: 8241140
213 results