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Page 1
Inhibition of ATR opposes glioblastoma invasion through disruption of cytoskeletal networks and integrin internalization via macropinocytosis.
Derby SJ, Dutton L, Strathdee KE, Stevenson K, Koessinger A, Jackson M, Tian Y, Yu W, Mclay K, Misquitta J, Alsharif S, Clarke CJ, Gilmour L, Thomason P, McGhee E, McGarrity-Cottrell CL, Vanderlinden A, Collis SJ, Rominyi O, Lemgruber L, Solecki G, Olson M, Winkler F, Carlin LM, Heiland DH, Inman GJ, Chalmers AJ, Norman JC, Carruthers R, Birch JL. Derby SJ, et al. Among authors: carlin lm. Neuro Oncol. 2024 Apr 5;26(4):625-639. doi: 10.1093/neuonc/noad210. Neuro Oncol. 2024. PMID: 37936324 Free PMC article.
Mitochondrial double-stranded RNA homeostasis depends on cell-cycle progression.
Xavier V, Martinelli S, Corbyn R, Pennie R, Rakovic K, Powley IR, Officer-Jones L, Ruscica V, Galloway A, Carlin LM, Cowling VH, Le Quesne J, Martinou JC, MacVicar T. Xavier V, et al. Among authors: carlin lm. Life Sci Alliance. 2024 Aug 29;7(11):e202402764. doi: 10.26508/lsa.202402764. Print 2024 Nov. Life Sci Alliance. 2024. PMID: 39209534 Free PMC article.
eIF4A1-dependent mRNAs employ purine-rich 5'UTR sequences to activate localised eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation.
Schmidt T, Dabrowska A, Waldron JA, Hodge K, Koulouras G, Gabrielsen M, Munro J, Tack DC, Harris G, McGhee E, Scott D, Carlin LM, Huang D, Le Quesne J, Zanivan S, Wilczynska A, Bushell M. Schmidt T, et al. Among authors: carlin lm. Nucleic Acids Res. 2023 Feb 28;51(4):1859-1879. doi: 10.1093/nar/gkad030. Nucleic Acids Res. 2023. PMID: 36727461 Free PMC article.
Omentum-derived matrix enables the study of metastatic ovarian cancer and stromal cell functions in a physiologically relevant environment.
Neilson LJ, Cartwright D, Risteli M, Jokinen EM, McGarry L, Sandvik T, Nikolatou K, Hodge K, Atkinson S, Vias M, Kay EJ, Brenton JD, Carlin LM, Bryant DM, Salo T, Zanivan S. Neilson LJ, et al. Among authors: carlin lm. Matrix Biol Plus. 2023 Nov 22;19-20:100136. doi: 10.1016/j.mbplus.2023.100136. eCollection 2023 Dec. Matrix Biol Plus. 2023. PMID: 38223308 Free PMC article.
Asbestos accelerates disease onset in a genetic model of malignant pleural mesothelioma.
Farahmand P, Gyuraszova K, Rooney C, Raffo-Iraolagoitia XL, Jayasekera G, Hedley A, Johnson E, Chernova T, Malviya G, Hall H, Monteverde T, Blyth K, Duffin R, Carlin LM, Lewis D, Le Quesne J, MacFarlane M, Murphy DJ. Farahmand P, et al. Among authors: carlin lm. Front Toxicol. 2023 Jun 27;5:1200650. doi: 10.3389/ftox.2023.1200650. eCollection 2023. Front Toxicol. 2023. PMID: 37441092 Free PMC article.
The eATP/P2×7R Axis Drives Quantum Dot-Nanoparticle Induced Neutrophil Recruitment in the Pulmonary Microcirculation.
Li C, Liu Q, Han L, Zhang H, Immler R, Rathkolb B, Secklehner J, de Angelis MH, Yildirim AÖ, Zeuschner D, Nicke A, Carlin LM, Sperandio M, Stoeger T, Rehberg M. Li C, et al. Among authors: carlin lm. Adv Sci (Weinh). 2024 Dec;11(45):e2404661. doi: 10.1002/advs.202404661. Epub 2024 Oct 4. Adv Sci (Weinh). 2024. PMID: 39364760 Free PMC article.
Multimodal decoding of human liver regeneration.
Matchett KP, Wilson-Kanamori JR, Portman JR, Kapourani CA, Fercoq F, May S, Zajdel E, Beltran M, Sutherland EF, Mackey JBG, Brice M, Wilson GC, Wallace SJ, Kitto L, Younger NT, Dobie R, Mole DJ, Oniscu GC, Wigmore SJ, Ramachandran P, Vallejos CA, Carragher NO, Saeidinejad MM, Quaglia A, Jalan R, Simpson KJ, Kendall TJ, Rule JA, Lee WM, Hoare M, Weston CJ, Marioni JC, Teichmann SA, Bird TG, Carlin LM, Henderson NC. Matchett KP, et al. Among authors: carlin lm. Nature. 2024 Jun;630(8015):158-165. doi: 10.1038/s41586-024-07376-2. Epub 2024 May 1. Nature. 2024. PMID: 38693268 Free PMC article.
Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function.
Santi A, Kay EJ, Neilson LJ, McGarry L, Lilla S, Mullin M, Paul NR, Fercoq F, Koulouras G, Rodriguez Blanco G, Athineos D, Mason S, Hughes M, Thomson G, Kieffer Y, Nixon C, Blyth K, Mechta-Grigoriou F, Carlin LM, Zanivan S. Santi A, et al. Among authors: carlin lm. Sci Signal. 2024 Mar 12;17(827):eade0580. doi: 10.1126/scisignal.ade0580. Epub 2024 Mar 12. Sci Signal. 2024. PMID: 38470957
Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils.
Fetit R, McLaren AS, White M, Mills ML, Falconer J, Cortes-Lavaud X, Gilroy K, Lannagan TRM, Ridgway RA, Nixon C, Naiker V, Njunge R, Clarke CJ, Whyte D, Kirschner K, Jackstadt R, Norman J, Carlin LM, Campbell AD, Sansom OJ, Steele CW. Fetit R, et al. Among authors: carlin lm. Cancer Res Commun. 2024 Feb 29;4(2):588-606. doi: 10.1158/2767-9764.CRC-23-0319. Cancer Res Commun. 2024. PMID: 38358352 Free PMC article.
Lung extracellular matrix modulates KRT5+ basal cell activity in pulmonary fibrosis.
Hewitt RJ, Puttur F, Gaboriau DCA, Fercoq F, Fresquet M, Traves WJ, Yates LL, Walker SA, Molyneaux PL, Kemp SV, Nicholson AG, Rice A, Roberts E, Lennon R, Carlin LM, Byrne AJ, Maher TM, Lloyd CM. Hewitt RJ, et al. Among authors: carlin lm. Nat Commun. 2023 Sep 27;14(1):6039. doi: 10.1038/s41467-023-41621-y. Nat Commun. 2023. PMID: 37758700 Free PMC article.
55 results