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Impact of the PI3K-alpha inhibitor alpelisib on everolimus resistance and somatostatin receptor expression in an orthotopic pancreatic NEC xenograft mouse model.
Mohan AM, Prasad S, Schmitz-Peiffer F, Lange C, Lukas M, Koziolek EJ, Albrecht J, Messroghli D, Stein U, Ilmer M, Wang K, Schober L, Reul A, Maurer J, Friemel J, Weber A, Zuellig RA, Hantel C, Fritsch R, Reincke M, Pacak K, Grossman AB, Auernhammer CJ, Beuschlein F, Brenner W, Beindorff N, Nölting S. Mohan AM, et al. Among authors: pacak k. Endocr Relat Cancer. 2023 Nov 30;31(1):e230041. doi: 10.1530/ERC-23-0041. Print 2024 Jan 1. Endocr Relat Cancer. 2023. PMID: 37943630
Metastatic Pheochromocytoma and Paraganglioma: Somatostatin Receptor 2 Expression, Genetics, and Therapeutic Responses.
Fischer A, Kloos S, Maccio U, Friemel J, Remde H, Fassnacht M, Pamporaki C, Eisenhofer G, Timmers HJLM, Robledo M, Fliedner SMJ, Wang K, Maurer J, Reul A, Zitzmann K, Bechmann N, Žygienė G, Richter S, Hantel C, Vetter D, Lehmann K, Mohr H, Pellegata NS, Ullrich M, Pietzsch J, Ziegler CG, Bornstein SR, Kroiss M, Reincke M, Pacak K, Grossman AB, Beuschlein F, Nölting S. Fischer A, et al. Among authors: pacak k. J Clin Endocrinol Metab. 2023 Sep 18;108(10):2676-2685. doi: 10.1210/clinem/dgad166. J Clin Endocrinol Metab. 2023. PMID: 36946182 Free PMC article.
Prediction of metastatic pheochromocytoma and paraganglioma: a machine learning modelling study using data from a cross-sectional cohort.
Pamporaki C, Berends AMA, Filippatos A, Prodanov T, Meuter L, Prejbisz A, Beuschlein F, Fassnacht M, Timmers HJLM, Nölting S, Abhyankar K, Constantinescu G, Kunath C, de Haas RJ, Wang K, Remde H, Bornstein SR, Januszewicz A, Robledo M, Lenders JWM, Kerstens MN, Pacak K, Eisenhofer G. Pamporaki C, et al. Among authors: pacak k. Lancet Digit Health. 2023 Sep;5(9):e551-e559. doi: 10.1016/S2589-7500(23)00094-8. Epub 2023 Jul 18. Lancet Digit Health. 2023. PMID: 37474439 Free PMC article.
Overview of recent guidelines and consensus statements on initial screening and management of phaeochromocytoma and paraganglioma in SDHx pathogenic variant carriers and patients.
Lussey-Lepoutre C, Pacak K, Grossman A, Taieb D, Amar L. Lussey-Lepoutre C, et al. Among authors: pacak k. Best Pract Res Clin Endocrinol Metab. 2024 Sep 7:101938. doi: 10.1016/j.beem.2024.101938. Online ahead of print. Best Pract Res Clin Endocrinol Metab. 2024. PMID: 39271377 Review.
EPAS1-related pheochromocytoma/paraganglioma.
Alzahrani AS, Alswailem M, Buffet A, Alghamdi B, Alobaid L, Alsagheir O, Al-Hindi H, Pacak K. Alzahrani AS, et al. Among authors: pacak k. Endocr Relat Cancer. 2024 Jun 10;31(8):e230303. doi: 10.1530/ERC-23-0303. Print 2024 Aug 1. Endocr Relat Cancer. 2024. PMID: 38767322 Review.
The evolutionary history of metastatic pancreatic neuroendocrine tumours reveals a therapy driven route to high-grade transformation.
Backman S, Botling J, Nord H, Ghosal S, Stålberg P, Juhlin CC, Almlöf J, Sundin A, Zhang L, Moens L, Eriksson B, Welin S, Hellman P, Skogseid B, Pacak K, Mollazadegan K, Åkerström T, Crona J. Backman S, et al. Among authors: pacak k. J Pathol. 2024 Dec;264(4):357-370. doi: 10.1002/path.6348. Epub 2024 Oct 3. J Pathol. 2024. PMID: 39360347
753 results