Trapani J - Search Results

1

Principles of CRISPR-Cas13 mismatch intolerance enable selective silencing of point-mutated oncogenic RNA with single-base precision.

Shembrey C, Yang R, Casan J, Hu W, Chen H, Singh GJ, Sadras T, Prasad K, Shortt J, Johnstone RW, Trapani JA, Ekert PG, Fareh M. Shembrey C, et al. Among authors: trapani ja. Sci Adv. 2024 Dec 20;10(51):eadl0731. doi: 10.1126/sciadv.adl0731. Epub 2024 Dec 18. Sci Adv. 2024. PMID: 39693429 Free PMC article.

2

Tissue-colonizing disseminated tumor cells secrete prostaglandin E2 to promote NK cell dysfunction and evade anti-metastatic immunity.

Pedde AM, Kim H, Donakonda S, Baumann T, Bayerl F, Meiser P, Hirschberger A, Klement C, Grassmann S, Öllinger R, Hüser N, Hartmann D, Laschinger M, Trapani JA, Zippelius A, Bald T, Wiedemann GM, Rad R, Sun JC, Höchst B, Böttcher JP. Pedde AM, et al. Among authors: trapani ja. Cell Rep. 2024 Nov 26;43(11):114855. doi: 10.1016/j.celrep.2024.114855. Epub 2024 Nov 13. Cell Rep. 2024. PMID: 39541209 Free article.

3

Spotlight on respiratory care, delirium, well-being and moral injury.

Trapani J, Stewart N, Eltaybani S, Vollam S. Trapani J, et al. Nurs Crit Care. 2024 Nov;29(6):1195-1198. doi: 10.1111/nicc.13189. Nurs Crit Care. 2024. PMID: 39470250 No abstract available.

4

Disruption of mitochondrial electron transport impairs urinary concentration via AMPK-dependent suppression of aquaporin 2.

Carty JS, Bessho R, Zuchowski Y, Trapani JB, Davidoff O, Kobayashi H, Roland JT, Watts JA, Terker AS, Bock F, Arroyo JP, Haase VH. Carty JS, et al. Among authors: trapani jb. JCI Insight. 2024 Nov 22;9(22):e182087. doi: 10.1172/jci.insight.182087. JCI Insight. 2024. PMID: 39361429 Free PMC article.

5

Cancer cell-specific PD-L1 expression is a predictor of poor outcome in patients with locally advanced oral cavity squamous cell carcinoma.

Wang M, Qin L, Thia K, Nguyen T, MacDonald S, Belobrov S, Kranz S, Goode D, Trapani JA, Wiesenfeld D, Neeson PJ. Wang M, et al. Among authors: trapani ja. J Immunother Cancer. 2024 Oct 2;12(10):e009617. doi: 10.1136/jitc-2024-009617. J Immunother Cancer. 2024. PMID: 39357980 Free PMC article.

6

Spotlight on BACCN Conference 2024: Celebrating the diversity in critical care education, research and clinical practice.

Eltaybani S, Credland N, Stewart N, Trapani J. Eltaybani S, et al. Among authors: trapani j. Nurs Crit Care. 2024 Sep;29(5):845-847. doi: 10.1111/nicc.13147. Nurs Crit Care. 2024. PMID: 39207044 No abstract available.

7

Spotlight on the psychological and emotional aspects of critical care.

Eltaybani S, Trapani J, Stewart N. Eltaybani S, et al. Among authors: trapani j. Nurs Crit Care. 2024 Jul;29(4):635-636. doi: 10.1111/nicc.13101. Nurs Crit Care. 2024. PMID: 39031792 No abstract available.

8

Pharmacologic inhibition of dipeptidyl peptidase 1 (cathepsin C) does not block in vitro granzyme-mediated target cell killing by CD8 T or NK cells.

Sutton VR, Watt SV, Akhlaghi H, Cipolla DC, Chen KJ, LaSala D, McDonald PP, Beavis PA, Munoz I, Hodel AW, Noori T, Voskoboinik I, Trapani JA. Sutton VR, et al. Among authors: trapani ja. Front Pharmacol. 2024 Jul 3;15:1396710. doi: 10.3389/fphar.2024.1396710. eCollection 2024. Front Pharmacol. 2024. PMID: 39021839 Free PMC article.

9

Single-base tiled screen unveils design principles of PspCas13b for potent and off-target-free RNA silencing.

Hu W, Kumar A, Ahmed SF, Qi S, Ma DKG, Chen H, Singh GJ, Casan JML, Haber M, Voskoboinik I, McKay MR, Trapani JA, Ekert PG, Fareh M. Hu W, et al. Among authors: trapani ja. Nat Struct Mol Biol. 2024 Nov;31(11):1702-1716. doi: 10.1038/s41594-024-01336-0. Epub 2024 Jul 1. Nat Struct Mol Biol. 2024. PMID: 38951623 Free PMC article.

10

CRISPR-Cas13b-mediated suppression of HBV replication and protein expression.

McCoullough LC, Fareh M, Hu W, Sozzi V, Makhlouf C, Droungas Y, Lee CL, Takawy M, Fabb SA, Payne TJ, Pouton CW, Netter HJ, Lewin SR, Purcell DF, Holmes JA, Trapani JA, Littlejohn M, Revill PA. McCoullough LC, et al. Among authors: trapani ja. J Hepatol. 2024 Nov;81(5):794-805. doi: 10.1016/j.jhep.2024.05.025. Epub 2024 May 28. J Hepatol. 2024. PMID: 38815932 Free article.

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