Flanagan T - Search Results

1

Contribution of the Dynamic Intestinal Absorption Model (Diamod) to the Development of a Patient-Centric Drug Formulation.

Moens F, Larsson A, De Blaiser A, Vandevijver G, Spreafico F, Nicolas JM, Lacombe L, Segregur D, Flanagan T, Berben P. Moens F, et al. Among authors: flanagan t. Mol Pharm. 2023 Dec 4;20(12):6197-6212. doi: 10.1021/acs.molpharmaceut.3c00607. Epub 2023 Nov 13. Mol Pharm. 2023. PMID: 37955627

2

Characterization of Aspirated Duodenal Fluids from Parkinson's Disease Patients.

de Waal T, Brouwers J, Berben P, Flanagan T, Tack J, Vandenberghe W, Vanuytsel T, Augustijns P. de Waal T, et al. Among authors: flanagan t. Pharmaceutics. 2023 Apr 14;15(4):1243. doi: 10.3390/pharmaceutics15041243. Pharmaceutics. 2023. PMID: 37111729 Free PMC article.

3

Impact of Acid-Reducing Agents on Gastrointestinal Physiology and Design of Biorelevant Dissolution Tests to Reflect These Changes.

Segregur D, Flanagan T, Mann J, Moir A, Karlsson EM, Hoch M, Carlile D, Sayah-Jeanne S, Dressman J. Segregur D, et al. Among authors: flanagan t. J Pharm Sci. 2019 Nov;108(11):3461-3477. doi: 10.1016/j.xphs.2019.06.021. Epub 2019 Jun 29. J Pharm Sci. 2019. PMID: 31265846 Review.

4

Developing Clinically Relevant Dissolution Specifications for Oral Drug Products-Industrial and Regulatory Perspectives.

McAllister M, Flanagan T, Boon K, Pepin X, Tistaert C, Jamei M, Abend A, Kotzagiorgis E, Mackie C. McAllister M, et al. Among authors: flanagan t. Pharmaceutics. 2019 Dec 23;12(1):19. doi: 10.3390/pharmaceutics12010019. Pharmaceutics. 2019. PMID: 31878006 Free PMC article.

5

Developing Clinically Relevant Dissolution Specifications (CRDSs) for Oral Drug Products: Virtual Webinar Series.

McAllister M, Flanagan T, Cole S, Abend A, Kotzagiorgis E, Limberg J, Mead H, Mangas-Sanjuan V, Dickinson PA, Moir A, Pepin X, Zhou D, Tistaert C, Dokoumetzidis A, Anand O, Le Merdy M, Turner DB, Griffin BT, Darwich A, Dressman J, Mackie C. McAllister M, et al. Among authors: flanagan t. Pharmaceutics. 2022 May 7;14(5):1010. doi: 10.3390/pharmaceutics14051010. Pharmaceutics. 2022. PMID: 35631595 Free PMC article.

6

Biopharmaceutical implications of excipient variability on drug dissolution from immediate release products.

Zarmpi P, Flanagan T, Meehan E, Mann J, Østergaard J, Fotaki N. Zarmpi P, et al. Among authors: flanagan t. Eur J Pharm Biopharm. 2020 Sep;154:195-209. doi: 10.1016/j.ejpb.2020.07.014. Epub 2020 Jul 16. Eur J Pharm Biopharm. 2020. PMID: 32681966

7

In Vivo Predictive Dissolution (IPD) and Biopharmaceutical Modeling and Simulation: Future Use of Modern Approaches and Methodologies in a Regulatory Context.

Lennernäs H, Lindahl A, Van Peer A, Ollier C, Flanagan T, Lionberger R, Nordmark A, Yamashita S, Yu L, Amidon GL, Fischer V, Sjögren E, Zane P, McAllister M, Abrahamsson B. Lennernäs H, et al. Among authors: flanagan t. Mol Pharm. 2017 Apr 3;14(4):1307-1314. doi: 10.1021/acs.molpharmaceut.6b00824. Epub 2017 Mar 1. Mol Pharm. 2017. PMID: 28195732

8

Impact of Food and Drink Administration Vehicles on Paediatric Formulation Performance Part 2: Dissolution of Montelukast Sodium and Mesalazine Formulations.

Martir J, Flanagan T, Mann J, Fotaki N. Martir J, et al. Among authors: flanagan t. AAPS PharmSciTech. 2020 Oct 15;21(7):287. doi: 10.1208/s12249-020-01815-9. AAPS PharmSciTech. 2020. PMID: 33063245 Free PMC article.

9

Justification of Drug Product Dissolution Rate and Drug Substance Particle Size Specifications Based on Absorption PBPK Modeling for Lesinurad Immediate Release Tablets.

Pepin XJ, Flanagan TR, Holt DJ, Eidelman A, Treacy D, Rowlings CE. Pepin XJ, et al. Mol Pharm. 2016 Sep 6;13(9):3256-69. doi: 10.1021/acs.molpharmaceut.6b00497. Epub 2016 Jul 27. Mol Pharm. 2016. PMID: 27438964

10

BCS-based biowaivers: Extension to paediatrics.

Martir J, Flanagan T, Mann J, Fotaki N. Martir J, et al. Among authors: flanagan t. Eur J Pharm Sci. 2020 Dec 1;155:105549. doi: 10.1016/j.ejps.2020.105549. Epub 2020 Sep 14. Eur J Pharm Sci. 2020. PMID: 32941998

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