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Illuminating protein space with a programmable generative model.
Ingraham JB, Baranov M, Costello Z, Barber KW, Wang W, Ismail A, Frappier V, Lord DM, Ng-Thow-Hing C, Van Vlack ER, Tie S, Xue V, Cowles SC, Leung A, Rodrigues JV, Morales-Perez CL, Ayoub AM, Green R, Puentes K, Oplinger F, Panwar NV, Obermeyer F, Root AR, Beam AL, Poelwijk FJ, Grigoryan G. Ingraham JB, et al. Among authors: cowles sc. Nature. 2023 Nov;623(7989):1070-1078. doi: 10.1038/s41586-023-06728-8. Epub 2023 Nov 15. Nature. 2023. PMID: 37968394 Free PMC article.
Alum-anchored intratumoral retention improves the tolerability and antitumor efficacy of type I interferon therapies.
Lutz EA, Agarwal Y, Momin N, Cowles SC, Palmeri JR, Duong E, Hornet V, Sheen A, Lax BM, Rothschilds AM, Irvine DJ, Spranger S, Wittrup KD. Lutz EA, et al. Among authors: cowles sc. Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2205983119. doi: 10.1073/pnas.2205983119. Epub 2022 Aug 29. Proc Natl Acad Sci U S A. 2022. PMID: 36037341 Free PMC article.