Niu MM - Search Results

1

Highly potent dual-targeting angiotensin-converting enzyme 2 (ACE2) and Neuropilin-1 (NRP1) peptides: A promising broad-spectrum therapeutic strategy against SARS-CoV-2 infection.

Mei S, Zou Y, Jiang S, Xue L, Wang Y, Jing H, Yang P, Niu MM, Li J, Yuan K, Zhang Y. Mei S, et al. Among authors: niu mm. Eur J Med Chem. 2024 Jan 5;263:115908. doi: 10.1016/j.ejmech.2023.115908. Epub 2023 Oct 31. Eur J Med Chem. 2024. PMID: 37981444

2

Discovery of a Dual Tubulin and Poly(ADP-Ribose) Polymerase-1 Inhibitor by Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking, and Biological Evaluation.

Zheng L, Ren R, Sun X, Zou Y, Shi Y, Di B, Niu MM. Zheng L, et al. Among authors: niu mm. J Med Chem. 2021 Nov 11;64(21):15702-15715. doi: 10.1021/acs.jmedchem.1c00932. Epub 2021 Oct 21. J Med Chem. 2021. PMID: 34670362

3

Highly Potent, Selective, Biostable, and Cell-Permeable Cyclic d-Peptide for Dual-Targeting Therapy of Lung Cancer.

Zhou Y, Zou Y, Yang M, Mei S, Liu X, Han H, Zhang CD, Niu MM. Zhou Y, et al. Among authors: niu mm. J Am Chem Soc. 2022 Apr 27;144(16):7117-7128. doi: 10.1021/jacs.1c12075. Epub 2022 Apr 13. J Am Chem Soc. 2022. PMID: 35417174

4

Dual-targeting cyclic peptides of receptor-binding domain (RBD) and main protease (Mpro) as potential drug leads for the treatment of SARS-CoV-2 infection.

Xu Z, Zou Y, Gao X, Niu MM, Li J, Xue L, Jiang S. Xu Z, et al. Among authors: niu mm. Front Pharmacol. 2022 Oct 19;13:1041331. doi: 10.3389/fphar.2022.1041331. eCollection 2022. Front Pharmacol. 2022. PMID: 36339564 Free PMC article.

5

Non-covalent cyclic peptides simultaneously targeting Mpro and NRP1 are highly effective against Omicron BA.2.75.

Yin S, Mei S, Li Z, Xu Z, Wu Y, Chen X, Liu D, Niu MM, Li J. Yin S, et al. Among authors: niu mm. Front Pharmacol. 2022 Nov 2;13:1037993. doi: 10.3389/fphar.2022.1037993. eCollection 2022. Front Pharmacol. 2022. PMID: 36408220 Free PMC article.

6

Identification of a Novel Potent CYP4Z1 Inhibitor Attenuating the Stemness of Breast Cancer Cells through Lead Optimization.

Yuan Y, Yao H, Zhou M, Ma X, Zhou Y, Xu J, Niu M, Yin J, Zheng L, Xu S. Yuan Y, et al. J Med Chem. 2022 Dec 8;65(23):15749-15769. doi: 10.1021/acs.jmedchem.2c01320. Epub 2022 Nov 22. J Med Chem. 2022. PMID: 36414390

7

Discovery of potent and noncovalent KRAS^G12D inhibitors: Structure-based virtual screening and biological evaluation.

Wang Y, Zhang H, Li J, Niu MM, Zhou Y, Qu Y. Wang Y, et al. Among authors: niu mm. Front Pharmacol. 2022 Dec 22;13:1094887. doi: 10.3389/fphar.2022.1094887. eCollection 2022. Front Pharmacol. 2022. PMID: 36618907 Free PMC article.

8

Discovery of dual S-RBD/NRP1-targeting peptides: structure-based virtual screening, synthesis, biological evaluation, and molecular dynamics simulation studies.

Hu C, Guo T, Zou Y, Gao J, Gao Y, Niu M, Xia Y, Shen X, Li J. Hu C, et al. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2212327. doi: 10.1080/14756366.2023.2212327. J Enzyme Inhib Med Chem. 2023. PMID: 37194732 Free PMC article.

9

Discovery of potent heat shock protein 90 (Hsp90) inhibitors: structure-based virtual screening, molecular dynamics simulation, and biological evaluation.

Xu Y, Zou Y, Zhou S, Niu MM, Zhang Y, Li J, Xu Z, Yang L. Xu Y, et al. Among authors: niu mm. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2220558. doi: 10.1080/14756366.2023.2220558. J Enzyme Inhib Med Chem. 2023. PMID: 37357755 Free PMC article.

10

Discovery and biological evaluation of novel CARM1/HDAC2 dual-targeting inhibitors with anti-prostate cancer agents.

Liang S, Geng Y, Niu MM, Zhang Y, He W, Li J, Yang L, Xu Z. Liang S, et al. Among authors: niu mm. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2241118. doi: 10.1080/14756366.2023.2241118. J Enzyme Inhib Med Chem. 2023. PMID: 37528657 Free PMC article.

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