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Arachidonic acid impairs natural killer cell functions by disrupting signaling pathways driven by activating receptors and reactive oxygen species.
Hammoud MK, Meena C, Dietze R, Hoffmann N, Szymanski W, Finkernagel F, Nist A, Stiewe T, Graumann J, von Strandmann EP, Müller R. Hammoud MK, et al. Among authors: graumann j. Cell Commun Signal. 2024 Nov 19;22(1):555. doi: 10.1186/s12964-024-01940-z. Cell Commun Signal. 2024. PMID: 39563446 Free PMC article.
NoxO1 regulates EGFR signaling by its interaction with Erbin.
Hebchen DM, Schader T, Spaeth M, Müller N, Graumann J, Schröder K. Hebchen DM, et al. Among authors: graumann j. Redox Biol. 2024 Nov;77:103396. doi: 10.1016/j.redox.2024.103396. Epub 2024 Oct 16. Redox Biol. 2024. PMID: 39426288 Free PMC article.
SIAH3 is frequently epigenetically silenced in cancer and regulates mitochondrial metabolism.
Deutschmeyer VE, Schlaudraff NA, Walesch SK, Moyer J, Sokol AM, Graumann J, Meissner W, Schneider M, Muley T, Helmbold P, Schwinn M, Richter AM, Schmitz ML, Dammann RH. Deutschmeyer VE, et al. Among authors: graumann j. Int J Cancer. 2025 Jan 15;156(2):353-367. doi: 10.1002/ijc.35202. Epub 2024 Sep 30. Int J Cancer. 2025. PMID: 39344659 Free PMC article.
A roadmap to the molecular human linking multiomics with population traits and diabetes subtypes.
Halama A, Zaghlool S, Thareja G, Kader S, Al Muftah W, Mook-Kanamori M, Sarwath H, Mohamoud YA, Stephan N, Ameling S, Pucic Baković M, Krumsiek J, Prehn C, Adamski J, Schwenk JM, Friedrich N, Völker U, Wuhrer M, Lauc G, Najafi-Shoushtari SH, Malek JA, Graumann J, Mook-Kanamori D, Schmidt F, Suhre K. Halama A, et al. Among authors: graumann j. Nat Commun. 2024 Aug 19;15(1):7111. doi: 10.1038/s41467-024-51134-x. Nat Commun. 2024. PMID: 39160153 Free PMC article.
Secretome Analysis Using Affinity Proteomics and Immunoassays: A Focus on Tumor Biology.
Beutgen VM, Shinkevich V, Pörschke J, Meena C, Steitz AM, Pogge von Strandmann E, Graumann J, Gómez-Serrano M. Beutgen VM, et al. Among authors: graumann j. Mol Cell Proteomics. 2024 Sep;23(9):100830. doi: 10.1016/j.mcpro.2024.100830. Epub 2024 Aug 13. Mol Cell Proteomics. 2024. PMID: 39147028 Free PMC article. Review.
BAG6 restricts pancreatic cancer progression by suppressing the release of IL33-presenting extracellular vesicles and the activation of mast cells.
Alashkar Alhamwe B, Ponath V, Alhamdan F, Dörsam B, Landwehr C, Linder M, Pauck K, Miethe S, Garn H, Finkernagel F, Brichkina A, Lauth M, Tiwari DK, Buchholz M, Bachurski D, Elmshäuser S, Nist A, Stiewe T, Pogge von Strandmann L, Szymański W, Beutgen V, Graumann J, Teply-Szymanski J, Keber C, Denkert C, Jacob R, Preußer C, Pogge von Strandmann E. Alashkar Alhamwe B, et al. Among authors: graumann j. Cell Mol Immunol. 2024 Aug;21(8):918-931. doi: 10.1038/s41423-024-01195-1. Epub 2024 Jun 28. Cell Mol Immunol. 2024. PMID: 38942797 Free PMC article.
DYRK1B blockade promotes tumoricidal macrophage activity in pancreatic cancer.
Brichkina A, Ems M, Suezov R, Singh R, Lutz V, Picard FSR, Nist A, Stiewe T, Graumann J, Daude M, Diederich WE, Finkernagel F, Chung HR, Bartsch DK, Roth K, Keber C, Denkert C, Huber M, Gress TM, Lauth M. Brichkina A, et al. Among authors: graumann j. Gut. 2024 Sep 9;73(10):1684-1701. doi: 10.1136/gutjnl-2023-331854. Gut. 2024. PMID: 38834297 Free PMC article.
118 results