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Page 1
A Novel Mouse Model for Cerebral Inflammatory Demyelination in X-Linked Adrenoleukodystrophy: Insights into Pathogenesis and Potential Therapeutic Targets.
Hashemi E, Srivastava IN, Aguirre A, Yoseph ET, Kaushal E, Awani A, Ryu JK, Akassoglou K, Talebian S, Chu P, Pisani L, Musolino P, Steinman L, Doyle K, Robinson WH, Sharpe O, Cayrol R, Orchard PJ, Lund T, Vogel H, Lenail M, Han MH, Bonkowsky JL, Van Haren KP. Hashemi E, et al. Among authors: awani a. Ann Neurol. 2024 Oct 28. doi: 10.1002/ana.27117. Online ahead of print. Ann Neurol. 2024. PMID: 39467011
Failure of metabolic checkpoint control during late-stage granulopoiesis drives neutropenia in reticular dysgenesis.
Wang W, Arreola M, Mathews T, DeVilbiss A, Zhao Z, Martin-Sandoval M, Mohammed A, Benegiamo G, Awani A, Goeminne L, Dever D, Nakauchi Y, Porteus MH, Pavel-Dinu M, Al-Herz W, Auwerx J, Morrison SJ, Weinacht KG. Wang W, et al. Among authors: awani a. Blood. 2024 Dec 26;144(26):2718-2734. doi: 10.1182/blood.2024024123. Blood. 2024. PMID: 39378586
A novel mouse model of cerebral adrenoleukodystrophy highlights NLRP3 activity in lesion pathogenesis.
Hashemi E, Narain Srivastava I, Aguirre A, Tilahan Yoseph E, Kaushal E, Awani A, Kyu Ryu J, Akassoglou K, Talebian S, Chu P, Pisani L, Musolino P, Steinman L, Doyle K, Robinson WH, Sharpe O, Cayrol R, Orchard P, Lund T, Vogel H, Lenail M, Han MH, Bonkowsky JL, Van Haren KP. Hashemi E, et al. Among authors: awani a. bioRxiv [Preprint]. 2023 Nov 10:2023.11.07.564025. doi: 10.1101/2023.11.07.564025. bioRxiv. 2023. PMID: 37986739 Free PMC article. Preprint.
A Phase 1 Study of Oral Vitamin D3 in Boys and Young Men With X-Linked Adrenoleukodystrophy.
Van Haren KP, Cunanan K, Awani A, Gu M, Peña D, Chromik LC, Považan M, Rossi NC, Goodman J, Sundaram V, Winterbottom J, Raymond GV, Cowan T, Enns GM, Waubant E, Steinman L, Barker PB, Spielman D, Fatemi A. Van Haren KP, et al. Among authors: awani a. Neurol Genet. 2023 Mar 31;9(2):e200061. doi: 10.1212/NXG.0000000000200061. eCollection 2023 Apr. Neurol Genet. 2023. PMID: 37090939 Free PMC article.
Peripheral T-Cells, B-Cells, and Monocytes from Multiple Sclerosis Patients Supplemented with High-Dose Vitamin D Show Distinct Changes in Gene Expression Profiles.
Kim D, Witt EE, Schubert S, Sotirchos E, Bhargava P, Mowry EM, Sachs K, Bilen B, Steinman L, Awani A, He Z, Calabresi PA, Van Haren K. Kim D, et al. Among authors: awani a. Nutrients. 2022 Nov 9;14(22):4737. doi: 10.3390/nu14224737. Nutrients. 2022. PMID: 36432424 Free PMC article. Clinical Trial.