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A novel mouse model of cerebral adrenoleukodystrophy highlights NLRP3 activity in lesion pathogenesis.
Hashemi E, Narain Srivastava I, Aguirre A, Tilahan Yoseph E, Kaushal E, Awani A, Kyu Ryu J, Akassoglou K, Talebian S, Chu P, Pisani L, Musolino P, Steinman L, Doyle K, Robinson WH, Sharpe O, Cayrol R, Orchard P, Lund T, Vogel H, Lenail M, Han MH, Bonkowsky JL, Van Haren KP. Hashemi E, et al. Among authors: chu p. bioRxiv [Preprint]. 2023 Nov 10:2023.11.07.564025. doi: 10.1101/2023.11.07.564025. bioRxiv. 2023. PMID: 37986739 Free PMC article. Preprint.
A Novel Mouse Model for Cerebral Inflammatory Demyelination in X-Linked Adrenoleukodystrophy: Insights into Pathogenesis and Potential Therapeutic Targets.
Hashemi E, Srivastava IN, Aguirre A, Yoseph ET, Kaushal E, Awani A, Ryu JK, Akassoglou K, Talebian S, Chu P, Pisani L, Musolino P, Steinman L, Doyle K, Robinson WH, Sharpe O, Cayrol R, Orchard PJ, Lund T, Vogel H, Lenail M, Han MH, Bonkowsky JL, Van Haren KP. Hashemi E, et al. Among authors: chu p. Ann Neurol. 2024 Oct 28. doi: 10.1002/ana.27117. Online ahead of print. Ann Neurol. 2024. PMID: 39467011
alpha(v)beta(3) Integrin in central nervous system tumors.
Lim M, Guccione S, Haddix T, Sims L, Cheshier S, Chu P, Vogel H, Harsh G. Lim M, et al. Among authors: chu p. Hum Pathol. 2005 Jun;36(6):665-9. doi: 10.1016/j.humpath.2005.03.014. Hum Pathol. 2005. PMID: 16021573
Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors.
Gholamin S, Mitra SS, Feroze AH, Liu J, Kahn SA, Zhang M, Esparza R, Richard C, Ramaswamy V, Remke M, Volkmer AK, Willingham S, Ponnuswami A, McCarty A, Lovelace P, Storm TA, Schubert S, Hutter G, Narayanan C, Chu P, Raabe EH, Harsh G 4th, Taylor MD, Monje M, Cho YJ, Majeti R, Volkmer JP, Fisher PG, Grant G, Steinberg GK, Vogel H, Edwards M, Weissman IL, Cheshier SH. Gholamin S, et al. Among authors: chu p. Sci Transl Med. 2017 Mar 15;9(381):eaaf2968. doi: 10.1126/scitranslmed.aaf2968. Sci Transl Med. 2017. PMID: 28298418 Free article.
A Clinical PET Imaging Tracer ([18F]DASA-23) to Monitor Pyruvate Kinase M2-Induced Glycolytic Reprogramming in Glioblastoma.
Beinat C, Patel CB, Haywood T, Murty S, Naya L, Castillo JB, Reyes ST, Phillips M, Buccino P, Shen B, Park JH, Koran MEI, Alam IS, James ML, Holley D, Halbert K, Gandhi H, He JQ, Granucci M, Johnson E, Liu DD, Uchida N, Sinha R, Chu P, Born DE, Warnock GI, Weissman I, Hayden-Gephart M, Khalighi M, Massoud TF, Iagaru A, Davidzon G, Thomas R, Nagpal S, Recht LD, Gambhir SS. Beinat C, et al. Among authors: chu p. Clin Cancer Res. 2021 Dec 1;27(23):6467-6478. doi: 10.1158/1078-0432.CCR-21-0544. Epub 2021 Sep 2. Clin Cancer Res. 2021. PMID: 34475101 Free PMC article.
Foci of Listeria monocytogenes persist in the bone marrow.
Hardy J, Chu P, Contag CH. Hardy J, et al. Among authors: chu p. Dis Model Mech. 2009 Jan-Feb;2(1-2):39-46. doi: 10.1242/dmm.000836. Epub 2008 Dec 22. Dis Model Mech. 2009. PMID: 19132117 Free PMC article.
A human brain vascular atlas reveals diverse mediators of Alzheimer's risk.
Yang AC, Vest RT, Kern F, Lee DP, Agam M, Maat CA, Losada PM, Chen MB, Schaum N, Khoury N, Toland A, Calcuttawala K, Shin H, Pálovics R, Shin A, Wang EY, Luo J, Gate D, Schulz-Schaeffer WJ, Chu P, Siegenthaler JA, McNerney MW, Keller A, Wyss-Coray T. Yang AC, et al. Among authors: chu p. Nature. 2022 Mar;603(7903):885-892. doi: 10.1038/s41586-021-04369-3. Epub 2022 Feb 14. Nature. 2022. PMID: 35165441 Free PMC article.
3,043 results