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Page 1
Sulfide oxidation promotes hypoxic angiogenesis and neovascularization.
Kumar R, Vitvitsky V, Seth P, Hiraki HL, Bell H, Andren A, Singhal R, Baker BM, Lyssiotis CA, Shah YM, Banerjee R. Kumar R, et al. Among authors: shah ym. bioRxiv [Preprint]. 2023 Mar 15:2023.03.14.532677. doi: 10.1101/2023.03.14.532677. bioRxiv. 2023. Update in: Nat Chem Biol. 2024 Oct;20(10):1294-1304. doi: 10.1038/s41589-024-01583-8. PMID: 36993187 Free PMC article. Updated. Preprint.
GTP signaling links metabolism, DNA repair, and responses to genotoxic stress.
Zhou W, Zhao Z, Lin A, Yang J, Xu J, Kari WR, Yang A, Li J, Solanki S, Speth J, Walker N, Scott AJ, Kothari AU, Yao Y, Peterson ER, Korimerla N, Werner CK, Liang J, Jacobson J, Palavalasa S, Obrien AM, Elaimy AL, Ferris SP, Zhao SG, Sarkaria JN, Győrffy B, Zhang S, Al-Holou WN, Umemura Y, Morgan MA, Lawrence TS, Lyssiotis CA, Peters-Golden M, Shah YM, Wahl DR. Zhou W, et al. Among authors: shah ym. bioRxiv [Preprint]. 2023 Apr 13:2023.04.12.536297. doi: 10.1101/2023.04.12.536297. bioRxiv. 2023. Update in: Cancer Discov. 2024 Jan 12;14(1):158-175. doi: 10.1158/2159-8290.CD-23-0437. PMID: 37090571 Free PMC article. Updated. Preprint.
BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III.
Chen B, Lynn-Nguyen TM, Jadhav P, Halligan BS, Rossiter NJ, Guerra RM, Koshkin S, Koo I, Morlacchi P, Hanna DA, Lin J, Banerjee R, Pagliarini DJ, Patterson AD, Mosalaganti S, Sexton JZ, Calì T, Lyssiotis CA, Shah YM. Chen B, et al. Among authors: shah ym. bioRxiv [Preprint]. 2024 Feb 4:2024.02.02.578646. doi: 10.1101/2024.02.02.578646. bioRxiv. 2024. PMID: 38352460 Free PMC article. Preprint.
Targeting PIKfyve-driven lipid homeostasis as a metabolic vulnerability in pancreatic cancer.
Cheng C, Hu J, Mannan R, Bhattacharyya R, Rossiter NJ, Magnuson B, Wisniewski JP, Zheng Y, Xiao L, Li C, Awad D, He T, Bao Y, Zhang Y, Cao X, Wang Z, Mehra R, Morlacchi P, Sahai V, di Magliano MP, Shah YM, Ding K, Qiao Y, Lyssiotis CA, Chinnaiyan AM. Cheng C, et al. Among authors: shah ym. bioRxiv [Preprint]. 2024 Mar 20:2024.03.18.585580. doi: 10.1101/2024.03.18.585580. bioRxiv. 2024. PMID: 38562800 Free PMC article. Preprint.
Recharacterization of RSL3 reveals that the selenoproteome is a druggable target in colorectal cancer.
DeAngelo SL, Zhao L, Dziechciarz S, Shin M, Solanki S, Balia A, El-Derany MO, Castillo C, Qin Y, Das NK, Bell HN, Paulo JA, Zhang Y, Rossiter NJ, McCulla EC, He J, Talukder I, Ng BW, Schafer ZT, Neamati N, Mancias JD, Koutmos M, Shah YM. DeAngelo SL, et al. Among authors: shah ym. bioRxiv [Preprint]. 2024 Aug 27:2024.03.29.587381. doi: 10.1101/2024.03.29.587381. bioRxiv. 2024. PMID: 38617233 Free PMC article. Preprint.
Structural enrichment attenuates colitis-associated colon cancer.
Sykes DJ, Solanki S, Chukkapalli S, Williams K, Newman EA, Resnicow K, Shah YM. Sykes DJ, et al. Among authors: shah ym. bioRxiv [Preprint]. 2024 Feb 16:2024.02.13.580099. doi: 10.1101/2024.02.13.580099. bioRxiv. 2024. PMID: 38405737 Free PMC article. Preprint.
Targeting PKCα decreases iron overload in diabetes.
El-Derany MO, Shah YM. El-Derany MO, et al. Among authors: shah ym. Blood. 2024 Sep 26;144(13):1359-1361. doi: 10.1182/blood.2024025677. Blood. 2024. PMID: 39325479 No abstract available.
SLC4A11 mediates ammonia import and promotes cancer stemness in hepatocellular carcinoma.
Elaimy AL, El-Derany MO, James J, Wang Z, Pearson AN, Holcomb EA, Huber AK, Gijón MA, Bell HN, Sanghvi VR, Frankel TL, Su GL, Tapper EB, Tai AW, Ramnath N, Centonze CP, Dobrosotskaya I, Moeller JA, Bryant AK, Elliott DA, Choi E, Evans JR, Cuneo KC, FitzGerald TJ, Wahl DR, Morgan MA, Chang DT, Wicha MS, Lawrence TS, Shah YM, Green MD. Elaimy AL, et al. Among authors: shah ym. JCI Insight. 2024 Sep 17:e184826. doi: 10.1172/jci.insight.184826. Online ahead of print. JCI Insight. 2024. PMID: 39287988 Free article.
179 results