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54 results

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Page 1
A phase 1 trial of AP30663, a KCa2 channel inhibitor in development for conversion of atrial fibrillation.
Yfanti C, Vestbjerg B, Van't Westende J, Edvardsson N, Monfort LM, Olesen MS, Bentzen BH, Grunnet M, Eveleens Maarse BC, Diness JG, Kemme MJB, Sørensen U, Moerland M, van Esdonk MJ, Klaassen ES, Gal P, Holst AG. Yfanti C, et al. Among authors: klaassen es. Br J Clin Pharmacol. 2024 Apr;90(4):1027-1035. doi: 10.1111/bcp.15973. Epub 2024 Jan 8. Br J Clin Pharmacol. 2024. PMID: 37990600 Clinical Trial.
Placebo- and amitriptyline-controlled evaluation of central nervous system effects of the NK1 receptor antagonist aprepitant and intravenous alcohol infusion at pseudo-steady state.
te Beek ET, Tatosian D, Majumdar A, Selverian D, Klaassen ES, Petty KJ, Gargano C, van Dyck K, McCrea J, Murphy G, van Gerven JM. te Beek ET, et al. Among authors: klaassen es. J Clin Pharmacol. 2013 Aug;53(8):846-56. doi: 10.1002/jcph.120. Epub 2013 Jun 18. J Clin Pharmacol. 2013. PMID: 23775877 Clinical Trial.
Renal Effects of Antisense-Mediated Inhibition of SGLT2.
van Meer L, Moerland M, van Dongen M, Goulouze B, de Kam M, Klaassen E, Cohen A, Burggraaf J. van Meer L, et al. J Pharmacol Exp Ther. 2016 Nov;359(2):280-289. doi: 10.1124/jpet.116.233809. Epub 2016 Sep 7. J Pharmacol Exp Ther. 2016. PMID: 27605629 Clinical Trial.
An anti-nicotinic cognitive challenge model using mecamylamine in comparison with the anti-muscarinic cognitive challenge using scopolamine.
Baakman AC, Alvarez-Jimenez R, Rissmann R, Klaassen ES, Stevens J, Goulooze SC, den Burger JCG, Swart EL, van Gerven JMA, Groeneveld GJ. Baakman AC, et al. Among authors: klaassen es. Br J Clin Pharmacol. 2017 Aug;83(8):1676-1687. doi: 10.1111/bcp.13268. Epub 2017 Apr 8. Br J Clin Pharmacol. 2017. PMID: 28217868 Free PMC article. Clinical Trial.
Glutathione-PEGylated liposomal methylprednisolone in comparison to free methylprednisolone: slow release characteristics and prolonged lymphocyte depression in a first-in-human study.
Kanhai KMS, Zuiker RGJA, Stavrakaki I, Gladdines W, Gaillard PJ, Klaassen ES, Groeneveld GJ. Kanhai KMS, et al. Among authors: klaassen es. Br J Clin Pharmacol. 2018 May;84(5):1020-1028. doi: 10.1111/bcp.13525. Epub 2018 Mar 9. Br J Clin Pharmacol. 2018. PMID: 29385232 Free PMC article. Clinical Trial.
Comprehensive, Multimodal Characterization of an Imiquimod-Induced Human Skin Inflammation Model for Drug Development.
van der Kolk T, Assil S, Rijneveld R, Klaassen ES, Feiss G, Florencia E, Prens EP, Burggraaf J, Moerland M, Rissmann R, van Doorn MBA. van der Kolk T, et al. Among authors: klaassen es. Clin Transl Sci. 2018 Nov;11(6):607-615. doi: 10.1111/cts.12563. Epub 2018 Jul 3. Clin Transl Sci. 2018. PMID: 29768709 Free PMC article. Clinical Trial.
Results of phase 2 trials exploring the safety and efficacy of omiganan in patients with human papillomavirus-induced genital lesions.
Rijsbergen M, Rijneveld R, Todd M, Feiss GL, Kouwenhoven STP, Quint KD, van Alewijk DCJG, de Koning MNC, Klaassen ES, Burggraaf J, Rissmann R, van Poelgeest MIE. Rijsbergen M, et al. Among authors: klaassen es. Br J Clin Pharmacol. 2020 Nov;86(11):2133-2143. doi: 10.1111/bcp.14181. Epub 2020 Sep 28. Br J Clin Pharmacol. 2020. PMID: 31755993 Free PMC article. Clinical Trial.
54 results