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Page 1
Discovery of RNA-Protein Molecular Clamps Using Proteome-Wide Stability Assays.
Goldstein SI, Fan AC, Wang Z, Naineni SK, Cencic R, Garcia-Gutierrez SB, Patel K, Huang S, Brown LE, Emili A, Porco JA Jr. Goldstein SI, et al. Among authors: naineni sk. bioRxiv [Preprint]. 2024 Dec 21:2024.04.19.590252. doi: 10.1101/2024.04.19.590252. bioRxiv. 2024. PMID: 38659867 Free PMC article. Preprint.
A second-generation eIF4A RNA helicase inhibitor exploits translational reprogramming as a vulnerability in triple-negative breast cancer.
Cencic R, Im YK, Naineni SK, Moustafa-Kamal M, Jovanovic P, Sabourin V, Annis MG, Robert F, Schmeing TM, Koromilas A, Paquet M, Teodoro JG, Huang S, Siegel PM, Topisirovic I, Ursini-Siegel J, Pelletier J. Cencic R, et al. Among authors: naineni sk. Proc Natl Acad Sci U S A. 2024 Jan 23;121(4):e2318093121. doi: 10.1073/pnas.2318093121. Epub 2024 Jan 17. Proc Natl Acad Sci U S A. 2024. PMID: 38232291 Free PMC article.
C8ORF88: A Novel eIF4E-Binding Protein.
Pugsley L, Naineni SK, Amiri M, Yanagiya A, Cencic R, Sonenberg N, Pelletier J. Pugsley L, et al. Among authors: naineni sk. Genes (Basel). 2023 Nov 14;14(11):2076. doi: 10.3390/genes14112076. Genes (Basel). 2023. PMID: 38003019 Free PMC article.
Exploring the targeting spectrum of rocaglates among eIF4A homologs.
Naineni SK, Cencic R, Robert F, Brown LE, Haque M, Scott-Talib J, Sénéchal P, Schmeing TM, Porco JA Jr, Pelletier J. Naineni SK, et al. RNA. 2023 Jun;29(6):826-835. doi: 10.1261/rna.079318.122. Epub 2023 Mar 7. RNA. 2023. PMID: 36882295 Free PMC article.
A forward genetic screen identifies modifiers of rocaglate responsiveness.
Shen L, Pugsley L, Cencic R, Wang H, Robert F, Naineni SK, Sahni A, Morin G, Zhang W, Nijnik A, Porco JA Jr, Langlais D, Huang S, Pelletier J. Shen L, et al. Among authors: naineni sk. Sci Rep. 2021 Sep 16;11(1):18516. doi: 10.1038/s41598-021-97765-8. Sci Rep. 2021. PMID: 34531456 Free PMC article.
Identification and characterization of hippuristanol-resistant mutants reveals eIF4A1 dependencies within mRNA 5' leader regions.
Steinberger J, Shen L, J Kiniry S, Naineni SK, Cencic R, Amiri M, Aboushawareb SAE, Chu J, Maïga RI, Yachnin BJ, Robert F, Sonenberg N, Baranov PV, Pelletier J. Steinberger J, et al. Among authors: naineni sk. Nucleic Acids Res. 2020 Sep 25;48(17):9521-9537. doi: 10.1093/nar/gkaa662. Nucleic Acids Res. 2020. PMID: 32766783 Free PMC article.
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