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Polyphyllin VI, a saponin from Trillium tschonoskii Maxim. induces apoptotic and autophagic cell death via the ROS triggered mTOR signaling pathway in non-small cell lung cancer.
Teng JF, Qin DL, Mei QB, Qiu WQ, Pan R, Xiong R, Zhao Y, Law BY, Wong VK, Tang Y, Yu CL, Zhang F, Wu JM, Wu AG. Teng JF, et al. Among authors: wu jm, wu ag. Pharmacol Res. 2019 Sep;147:104396. doi: 10.1016/j.phrs.2019.104396. Epub 2019 Aug 9. Pharmacol Res. 2019. PMID: 31404628
Lychee seed polyphenol protects the blood-brain barrier through inhibiting Aβ(25-35)-induced NLRP3 inflammasome activation via the AMPK/mTOR/ULK1-mediated autophagy in bEnd.3 cells and APP/PS1 mice.
Xiong R, Zhou XG, Tang Y, Wu JM, Sun YS, Teng JF, Pan R, Law BY, Zhao Y, Qiu WQ, Wang XL, Liu S, Wang YL, Yu L, Yu CL, Mei QB, Qin DL, Wu AG. Xiong R, et al. Among authors: wu jm, wu ag. Phytother Res. 2021 Feb;35(2):954-973. doi: 10.1002/ptr.6849. Epub 2020 Sep 6. Phytother Res. 2021. PMID: 32893437
174 results