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Amyloid β synaptotoxicity is Wnt-PCP dependent and blocked by fasudil.
Sellers KJ, Elliott C, Jackson J, Ghosh A, Ribe E, Rojo AI, Jarosz-Griffiths HH, Watson IA, Xia W, Semenov M, Morin P, Hooper NM, Porter R, Preston J, Al-Shawi R, Baillie G, Lovestone S, Cuadrado A, Harte M, Simons P, Srivastava DP, Killick R. Sellers KJ, et al. Among authors: morin p. Alzheimers Dement. 2018 Mar;14(3):306-317. doi: 10.1016/j.jalz.2017.09.008. Epub 2017 Oct 19. Alzheimers Dement. 2018. PMID: 29055813 Free PMC article.
A role for APP in Wnt signalling links synapse loss with β-amyloid production.
Elliott C, Rojo AI, Ribe E, Broadstock M, Xia W, Morin P, Semenov M, Baillie G, Cuadrado A, Al-Shawi R, Ballard CG, Simons P, Killick R. Elliott C, et al. Among authors: morin p. Transl Psychiatry. 2018 Sep 20;8(1):179. doi: 10.1038/s41398-018-0231-6. Transl Psychiatry. 2018. PMID: 30232325 Free PMC article.
Rule-Based Identification of Individuals with Mild Cognitive Impairment or Alzheimer's Disease Using Clinical Notes from the United States Veterans Affairs Healthcare System.
Aguilar BJ, Miller D, Jasuja G, Li X, Shishova E, O'Connor MK, Nguyen A, Morin P, Berlowitz D, Zhang R, Monfared AAT, Zhang Q, Xia W. Aguilar BJ, et al. Among authors: morin p. Neurol Ther. 2023 Dec;12(6):2067-2078. doi: 10.1007/s40120-023-00540-2. Epub 2023 Sep 25. Neurol Ther. 2023. PMID: 37747662 Free PMC article.
937 results