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92 results

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Page 1
Dual targeting of cancer metabolome and stress antigens affects transcriptomic heterogeneity and efficacy of engineered T cells.
Hernández-López P, van Diest E, Brazda P, Heijhuurs S, Meringa A, Hoorens van Heyningen L, Riillo C, Schwenzel C, Zintchenko M, Johanna I, Nicolasen MJT, Cleven A, Kluiver TA, Millen R, Zheng J, Karaiskaki F, Straetemans T, Clevers H, de Bree R, Stunnenberg HG, Peng WC, Roodhart J, Minguet S, Sebestyén Z, Beringer DX, Kuball J. Hernández-López P, et al. Among authors: cleven a. Nat Immunol. 2024 Jan;25(1):88-101. doi: 10.1038/s41590-023-01665-0. Epub 2023 Nov 27. Nat Immunol. 2024. PMID: 38012415
Uncovering the mode of action of engineered T cells in patient cancer organoids.
Dekkers JF, Alieva M, Cleven A, Keramati F, Wezenaar AKL, van Vliet EJ, Puschhof J, Brazda P, Johanna I, Meringa AD, Rebel HG, Buchholz MB, Barrera Román M, Zeeman AL, de Blank S, Fasci D, Geurts MH, Cornel AM, Driehuis E, Millen R, Straetemans T, Nicolasen MJT, Aarts-Riemens T, Ariese HCR, Johnson HR, van Ineveld RL, Karaiskaki F, Kopper O, Bar-Ephraim YE, Kretzschmar K, Eggermont AMM, Nierkens S, Wehrens EJ, Stunnenberg HG, Clevers H, Kuball J, Sebestyen Z, Rios AC. Dekkers JF, et al. Among authors: cleven a. Nat Biotechnol. 2023 Jan;41(1):60-69. doi: 10.1038/s41587-022-01397-w. Epub 2022 Jul 25. Nat Biotechnol. 2023. PMID: 35879361 Free PMC article.
RhoB Mediates Phosphoantigen Recognition by Vγ9Vδ2 T Cell Receptor.
Sebestyen Z, Scheper W, Vyborova A, Gu S, Rychnavska Z, Schiffler M, Cleven A, Chéneau C, van Noorden M, Peigné CM, Olive D, Lebbink RJ, Oostvogels R, Mutis T, Schuurhuis GJ, Adams EJ, Scotet E, Kuball J. Sebestyen Z, et al. Among authors: cleven a. Cell Rep. 2016 May 31;15(9):1973-85. doi: 10.1016/j.celrep.2016.04.081. Epub 2016 May 19. Cell Rep. 2016. PMID: 27210746 Free PMC article.
Recurrent ETV3::NCOA2 fusions and MAPK pathway mutations in indeterminate dendritic cell histiocytosis.
Kemps PG, Woei-A-Jin FJSH, Quint KD, van den Bos C, Naeije L, van Laar JA, Vanden Bempt I, Koudijs MJ, Vorderman RHP, Stelloo E, Swennenhuis JF, Bruggink AH, Hebeda KM, Scheijde-Vermeulen MA, Diercks GF, Verdijk RM, Jansen PM, Hauben E, Tousseyn T, Cleven AH, van Wezel T, van Halteren AGS, Hogendoorn PCW. Kemps PG, et al. Among authors: cleven ah. Blood Adv. 2024 Sep 24:bloodadvances.2024013696. doi: 10.1182/bloodadvances.2024013696. Online ahead of print. Blood Adv. 2024. PMID: 39361730 No abstract available.
Recurrent CLTC::SYK fusions and CSF1R mutations in juvenile xanthogranuloma of soft tissue.
Kemps PG, Baelde HJ, Vorderman RHP, Stelloo E, Swennenhuis JF, Szuhai K, Lamers MH, Kenkhuis B, Al-Hussaini M, Briaire-de Bruijn IH, Lam SW, Bovée JVMG, Cleven AHG, Verdijk RM, van Noesel CJM, van Dijk MR, Scheijde-Vermeulen MA, Bruggink AH, van Laar JAM, de Vries ACH, Tissing WJE, van den Bos C, von Deimling A, van Wezel T, van Halteren AGS, Hogendoorn PCW. Kemps PG, et al. Among authors: cleven ahg. Blood. 2024 Dec 5;144(23):2439-2455. doi: 10.1182/blood.2024025127. Blood. 2024. PMID: 39316650
Odontogenic Myxomas Harbor Recurrent Copy Number Alterations and a Distinct Methylation Signature.
Kleijn TG, Ameline B, Schreuder WH, Kooistra W, Doff JJ, Witjes M, Pichardo SEC, Lausová T, Koppes SA, van den Hout MFCM, van Engen-van Grunsven ICH, Flucke UE, de Lange J, Szuhai K, Briaire-de Bruijn IH, Savci-Heijink DC, Suurmeijer AJH, Bovée JVMG, von Deimling A, Baumhoer D, Cleven AHG. Kleijn TG, et al. Among authors: cleven ahg. Am J Surg Pathol. 2024 Oct 1;48(10):1224-1232. doi: 10.1097/PAS.0000000000002293. Epub 2024 Oct 16. Am J Surg Pathol. 2024. PMID: 39289817
Levels of circulating tumor DNA correlate with tumor volume in gastro-intestinal stromal tumors: an exploratory long-term follow-up study.
Bleckman RF, Haag CMSC, Rifaela N, Beukema G, Mathijssen RHJ, Steeghs N, Gelderblom H, Desar IME, Cleven A, Ter Elst A, Schuuring E, Reyners AKL. Bleckman RF, et al. Among authors: cleven a. Mol Oncol. 2024 Nov;18(11):2658-2667. doi: 10.1002/1878-0261.13644. Epub 2024 May 24. Mol Oncol. 2024. PMID: 38790141 Free PMC article.
Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCL.
Eken JA, Koning MT, Kupcova K, Sepúlveda Yáñez JH, de Groen RAL, Quinten E, Janssen J, van Bergen CAM, Vermaat JSP, Cleven A, Navarrete MA, Ylstra B, de Jong D, Havranek O, Jumaa H, Veelken H. Eken JA, et al. Among authors: cleven a. J Exp Med. 2024 May 6;221(5):e20230941. doi: 10.1084/jem.20230941. Epub 2024 Mar 21. J Exp Med. 2024. PMID: 38512136 Free PMC article.
92 results