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VTA dopamine neurons are hyperexcitable in 3xTg-AD mice due to casein kinase 2-dependent SK channel dysfunction.
Blankenship HE, Carter KA, Cassidy NT, Markiewicz AN, Thellmann MI, Sharpe AL, Freeman WM, Beckstead MJ. Blankenship HE, et al. Among authors: freeman wm. bioRxiv [Preprint]. 2023 Nov 17:2023.11.16.567486. doi: 10.1101/2023.11.16.567486. bioRxiv. 2023. Update in: Nat Commun. 2024 Nov 8;15(1):9673. doi: 10.1038/s41467-024-53891-1 PMID: 38014232 Free PMC article. Updated. Preprint.
Inducible cell-specific mouse models for paired epigenetic and transcriptomic studies of microglia and astroglia.
Chucair-Elliott AJ, Ocañas SR, Stanford DR, Ansere VA, Buettner KB, Porter H, Eliason NL, Reid JJ, Sharpe AL, Stout MB, Beckstead MJ, Miller BF, Richardson A, Freeman WM. Chucair-Elliott AJ, et al. Among authors: freeman wm. Commun Biol. 2020 Nov 19;3(1):693. doi: 10.1038/s42003-020-01418-x. Commun Biol. 2020. PMID: 33214681 Free PMC article.
Microglial MHC-I induction with aging and Alzheimer's is conserved in mouse models and humans.
Kellogg CM, Pham K, Machalinski AH, Porter HL, Blankenship HE, Tooley K, Stout MB, Rice HC, Sharpe AL, Beckstead MJ, Chucair-Elliott AJ, Ocañas SR, Freeman WM. Kellogg CM, et al. Among authors: freeman wm. bioRxiv [Preprint]. 2023 Jun 2:2023.03.07.531435. doi: 10.1101/2023.03.07.531435. bioRxiv. 2023. Update in: Geroscience. 2023 Oct;45(5):3019-3043. doi: 10.1007/s11357-023-00859-6 PMID: 36945372 Free PMC article. Updated. Preprint.
Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer's disease.
Ocañas SR, Pham KD, Cox JEJ, Keck AW, Ko S, Ampadu FA, Porter HL, Ansere VA, Kulpa A, Kellogg CM, Machalinski AH, Chucair-Elliott AJ, Freeman WM. Ocañas SR, et al. Among authors: freeman wm. bioRxiv [Preprint]. 2023 Jun 1:2023.03.07.531562. doi: 10.1101/2023.03.07.531562. bioRxiv. 2023. Update in: J Neuroinflammation. 2023 Aug 16;20(1):188. doi: 10.1186/s12974-023-02870-2 PMID: 36945656 Free PMC article. Updated. Preprint.
Microglial MHC-I induction with aging and Alzheimer's is conserved in mouse models and humans.
Kellogg CM, Pham K, Machalinski AH, Porter HL, Blankenship HE, Tooley KB, Stout MB, Rice HC, Sharpe AL, Beckstead MJ, Chucair-Elliott AJ, Ocañas SR, Freeman WM. Kellogg CM, et al. Among authors: freeman wm. Geroscience. 2023 Oct;45(5):3019-3043. doi: 10.1007/s11357-023-00859-6. Epub 2023 Jul 1. Geroscience. 2023. PMID: 37393197 Free PMC article.
Correction to: Microglial MHC‑I induction with aging and Alzheimer's is conserved in mouse models and humans.
Kellogg CM, Pham K, Machalinski AH, Porter HL, Blankenship HE, Tooley KB, Stout MB, Rice HC, Sharpe AL, Beckstead MJ, Chucair-Elliott AJ, Ocañas SR, Freeman WM. Kellogg CM, et al. Among authors: freeman wm. Geroscience. 2023 Oct;45(5):3101-3102. doi: 10.1007/s11357-023-00881-8. Geroscience. 2023. PMID: 37556087 Free PMC article. No abstract available.
Consistent specificity and efficiency of tamoxifen-mediated cre induction across ages.
Kellogg CM, Pham K, Ko S, Cox JEJ, Machalinski AH, Stout MB, Sharpe AL, Beckstead MJ, Chucair-Elliott AJ, Ocañas SR, Freeman WM. Kellogg CM, et al. Among authors: freeman wm. bioRxiv [Preprint]. 2023 Sep 22:2023.09.19.558482. doi: 10.1101/2023.09.19.558482. bioRxiv. 2023. Update in: iScience. 2023 Nov 09;26(12):108413. doi: 10.1016/j.isci.2023.108413 PMID: 37781585 Free PMC article. Updated. Preprint.
171 results