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CerS6-dependent ceramide synthesis in hypothalamic neurons promotes ER/mitochondrial stress and impairs glucose homeostasis in obese mice.
Hammerschmidt P, Steculorum SM, Bandet CL, Del Río-Martín A, Steuernagel L, Kohlhaas V, Feldmann M, Varela L, Majcher A, Quatorze Correia M, Klar RFU, Bauder CA, Kaya E, Porniece M, Biglari N, Sieben A, Horvath TL, Hornemann T, Brodesser S, Brüning JC. Hammerschmidt P, et al. Among authors: sieben a. Nat Commun. 2023 Nov 29;14(1):7824. doi: 10.1038/s41467-023-42595-7. Nat Commun. 2023. PMID: 38016943 Free PMC article.
Large-scale CSF proteome profiling identifies biomarkers for accurate diagnosis of Frontotemporal Dementia.
Hok-A-Hin YS, Vermunt L, Peeters CFW, van der Ende EL, de Boer SCM, Meeter LH, van Swieten JC, Hu WT, Lleó A, Alcolea D, Engelborghs S, Sieben A, Chen-Plotkin A, Irwin DJ, van der Flier WM, Pijnenburg YAL, Teunissen CE, Del Campo M. Hok-A-Hin YS, et al. Among authors: sieben a. medRxiv [Preprint]. 2024 Aug 20:2024.08.19.24312100. doi: 10.1101/2024.08.19.24312100. medRxiv. 2024. PMID: 39228745 Free PMC article. Preprint.
Brain age as a biomarker for pathological versus healthy ageing - a REMEMBER study.
Wittens MMJ, Denissen S, Sima DM, Fransen E, Niemantsverdriet E, Bastin C, Benoit F, Bergmans B, Bier JC, de Deyn PP, Deryck O, Hanseeuw B, Ivanoiu A, Picard G, Ribbens A, Salmon E, Segers K, Sieben A, Struyfs H, Thiery E, Tournoy J, van Binst AM, Versijpt J, Smeets D, Bjerke M, Nagels G, Engelborghs S. Wittens MMJ, et al. Among authors: sieben a. Alzheimers Res Ther. 2024 Jun 14;16(1):128. doi: 10.1186/s13195-024-01491-y. Alzheimers Res Ther. 2024. PMID: 38877568 Free PMC article.
MAPT H2 haplotype and risk of Pick's disease in the Pick's disease International Consortium: a genetic association study.
Valentino RR, Scotton WJ, Roemer SF, Lashley T, Heckman MG, Shoai M, Martinez-Carrasco A, Tamvaka N, Walton RL, Baker MC, Macpherson HL, Real R, Soto-Beasley AI, Mok K, Revesz T, Christopher EA, DeTure M, Seeley WW, Lee EB, Frosch MP, Molina-Porcel L, Gefen T, Redding-Ochoa J, Ghetti B, Robinson AC, Kobylecki C, Rowe JB, Beach TG, Teich AF, Keith JL, Bodi I, Halliday GM, Gearing M, Arzberger T, Morris CM, White CL 3rd, Mechawar N, Boluda S, MacKenzie IR, McLean C, Cykowski MD, Wang SJ, Graff C, Nagra RM, Kovacs GG, Giaccone G, Neumann M, Ang LC, Carvalho A, Morris HR, Rademakers R, Hardy JA, Dickson DW, Rohrer JD, Ross OA; Pick's disease International Consortium. Valentino RR, et al. Lancet Neurol. 2024 May;23(5):487-499. doi: 10.1016/S1474-4422(24)00083-8. Lancet Neurol. 2024. PMID: 38631765 Free article.
CSF proteome profiling reveals biomarkers to discriminate dementia with Lewy bodies from Alzheimer´s disease.
Del Campo M, Vermunt L, Peeters CFW, Sieben A, Hok-A-Hin YS, Lleó A, Alcolea D, van Nee M, Engelborghs S, van Alphen JL, Arezoumandan S, Chen-Plotkin A, Irwin DJ, van der Flier WM, Lemstra AW, Teunissen CE. Del Campo M, et al. Among authors: sieben a. Nat Commun. 2023 Sep 13;14(1):5635. doi: 10.1038/s41467-023-41122-y. Nat Commun. 2023. PMID: 37704597 Free PMC article.
115 results