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A phase I oncolytic virus trial with vesicular stomatitis virus expressing human interferon beta and tyrosinase related protein 1 administered intratumorally and intravenously in uveal melanoma: safety, efficacy, and T cell responses.
Smith KER, Peng KW, Pulido JS, Weisbrod AJ, Strand CA, Allred JB, Newsom AN, Zhang L, Packiriswamy N, Kottke T, Tonne JM, Moore M, Montane HN, Kottschade LA, McWilliams RR, Dudek AZ, Yan Y, Dimou A, Markovic SN, Federspiel MJ, Vile RG, Dronca RS, Block MS. Smith KER, et al. Among authors: kottke t. Front Immunol. 2023 Oct 31;14:1279387. doi: 10.3389/fimmu.2023.1279387. eCollection 2023. Front Immunol. 2023. PMID: 38022659 Free PMC article. Clinical Trial.
Cell carriers for oncolytic viruses: Fed Ex for cancer therapy.
Willmon C, Harrington K, Kottke T, Prestwich R, Melcher A, Vile R. Willmon C, et al. Among authors: kottke t. Mol Ther. 2009 Oct;17(10):1667-76. doi: 10.1038/mt.2009.194. Epub 2009 Aug 18. Mol Ther. 2009. PMID: 19690519 Free PMC article. Review.
Oncolytic virus-derived type I interferon restricts CAR T cell therapy.
Evgin L, Huff AL, Wongthida P, Thompson J, Kottke T, Tonne J, Schuelke M, Ayasoufi K, Driscoll CB, Shim KG, Reynolds P, Monie DD, Johnson AJ, Coffey M, Young SL, Archer G, Sampson J, Pulido J, Perez LS, Vile R. Evgin L, et al. Among authors: kottke t. Nat Commun. 2020 Jun 24;11(1):3187. doi: 10.1038/s41467-020-17011-z. Nat Commun. 2020. PMID: 32581235 Free PMC article.
459 results