Intraluminal delivery of thrombospondin-2 small interfering RNA inhibits the vascular response to injury in a rat carotid balloon angioplasty model.
Bodewes TC, Johnson JM, Auster M, Huynh C, Muralidharan S, Contreras M, LoGerfo FW, Pradhan-Nabzdyk L.
Bodewes TC, et al. Among authors: huynh c.
FASEB J. 2017 Jan;31(1):109-119. doi: 10.1096/fj.201600501R. Epub 2016 Sep 26.
FASEB J. 2017.
PMID: 27671229
Free PMC article.
In summary, these data demonstrate effective siRNA transfection of the injured arterial wall and provide a clinically effective and translationally applicable therapeutic strategy that involves nonviral siRNA delivery to ameliorate the response to vascular injury.-Bodewes, T. …
In summary, these data demonstrate effective siRNA transfection of the injured arterial wall and provide a clinically effective and translat …