Chhonker YS - Search Results

1

Blood-stage antimalarial activity, favourable metabolic stability and in vivo toxicity of novel piperazine linked 7-chloroquinoline-triazole conjugates.

Uddin A, Gupta S, Shoaib R, Aneja B, Irfan I, Gupta K, Rawat N, Combrinck J, Kumar B, Aleem M, Hasan P, Joshi MC, Chhonker YS, Zahid M, Hussain A, Pandey K, Alajmi MF, Murry DJ, Egan TJ, Singh S, Abid M. Uddin A, et al. Among authors: chhonker ys. Eur J Med Chem. 2024 Jan 15;264:115969. doi: 10.1016/j.ejmech.2023.115969. Epub 2023 Nov 25. Eur J Med Chem. 2024. PMID: 38039787

2

Synthesis, biological evaluation, and metabolic stability of phenazine derivatives as antibacterial agents.

Krishnaiah M, de Almeida NR, Udumula V, Song Z, Chhonker YS, Abdelmoaty MM, do Nascimento VA, Murry DJ, Conda-Sheridan M. Krishnaiah M, et al. Among authors: chhonker ys. Eur J Med Chem. 2018 Jan 1;143:936-947. doi: 10.1016/j.ejmech.2017.11.026. Epub 2017 Nov 9. Eur J Med Chem. 2018. PMID: 29227933

3

From dopamine 4 to sigma 1: Synthesis, SAR and biological characterization of a piperidine scaffold of σ1 modulators.

Tolentino KT, Mashinson V, Sharma MK, Chhonker YS, Murry DJ, Hopkins CR. Tolentino KT, et al. Among authors: chhonker ys. Eur J Med Chem. 2022 Dec 15;244:114840. doi: 10.1016/j.ejmech.2022.114840. Epub 2022 Oct 14. Eur J Med Chem. 2022. PMID: 36283180

4

Aldo-Keto Reductase 1C3 Inhibitor Prodrug Improves Pharmacokinetic Profile and Demonstrates In Vivo Efficacy in a Prostate Cancer Xenograft Model.

Maddeboina K, Jonnalagadda SK, Morsy A, Duan L, Chhonker YS, Murry DJ, Penning TM, Trippier PC. Maddeboina K, et al. Among authors: chhonker ys. J Med Chem. 2023 Jul 27;66(14):9894-9915. doi: 10.1021/acs.jmedchem.3c00732. Epub 2023 Jul 10. J Med Chem. 2023. PMID: 37428858

5

Bioanalytical method development and validation of moxidectin in plasma by LC-MS/MS: Application to in vitro metabolism.

Chhonker YS, Sleightholm RL, Murry DJ. Chhonker YS, et al. Biomed Chromatogr. 2019 Feb;33(2):e4389. doi: 10.1002/bmc.4389. Epub 2018 Oct 30. Biomed Chromatogr. 2019. PMID: 30238696

6

Quantification of eicosanoids and their metabolites in biological matrices: a review.

Chhonker YS, Bala V, Murry DJ. Chhonker YS, et al. Bioanalysis. 2018 Dec;10(24):2027-2046. doi: 10.4155/bio-2018-0173. Epub 2018 Nov 6. Bioanalysis. 2018. PMID: 30412686 Free PMC article. Review.

7

In Vivo Evaluation of Isoprenoid Triazole Bisphosphonate Inhibitors of Geranylgeranyl Diphosphate Synthase: Impact of Olefin Stereochemistry on Toxicity and Biodistribution.

Haney SL, Chhonker YS, Varney ML, Talmon G, Smith LM, Murry DJ, Holstein SA. Haney SL, et al. Among authors: chhonker ys. J Pharmacol Exp Ther. 2019 Nov;371(2):327-338. doi: 10.1124/jpet.119.258624. Epub 2019 Aug 16. J Pharmacol Exp Ther. 2019. PMID: 31420526 Free PMC article.

8

Simultaneous Quantitation of S(+)- and R(-)-Baclofen and Its Metabolite in Human Plasma and Cerebrospinal Fluid using LC-APCI-MS/MS: An Application for Clinical Studies.

He Q, Chhonker YS, McLaughlin MJ, Murry DJ. He Q, et al. Among authors: chhonker ys. Molecules. 2020 Jan 8;25(2):250. doi: 10.3390/molecules25020250. Molecules. 2020. PMID: 31936209 Free PMC article.

9

Synthesis and Antichlamydial Activity of Molecules Based on Dysregulators of Cylindrical Proteases.

Seleem MA, Rodrigues de Almeida N, Chhonker YS, Murry DJ, Guterres ZDR, Blocker AM, Kuwabara S, Fisher DJ, Leal ES, Martinefski MR, Bollini M, Monge ME, Ouellette SP, Conda-Sheridan M. Seleem MA, et al. Among authors: chhonker ys. J Med Chem. 2020 Apr 23;63(8):4370-4387. doi: 10.1021/acs.jmedchem.0c00371. Epub 2020 Apr 15. J Med Chem. 2020. PMID: 32227948 Free PMC article.

10

A Simultaneous Extraction/Derivatization Strategy for Quantitation of Vitamin D in Dried Blood Spots Using LC-MS/MS: Application to Biomarker Study in Subjects Tested for SARS-CoV-2.

Chhonker YS, Ahmed N, Johnston CM, Barnabas RV, Murry DJ. Chhonker YS, et al. Int J Mol Sci. 2023 Mar 13;24(6):5489. doi: 10.3390/ijms24065489. Int J Mol Sci. 2023. PMID: 36982565 Free PMC article.

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