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Astaxanthin and meclizine extend lifespan in UM-HET3 male mice; fisetin, SG1002 (hydrogen sulfide donor), dimethyl fumarate, mycophenolic acid, and 4-phenylbutyrate do not significantly affect lifespan in either sex at the doses and schedules used.
Harrison DE, Strong R, Reifsnyder P, Rosenthal N, Korstanje R, Fernandez E, Flurkey K, Ginsburg BC, Murrell MD, Javors MA, Lopez-Cruzan M, Nelson JF, Willcox BJ, Allsopp R, Watumull DM, Watumull DG, Cortopassi G, Kirkland JL, Tchkonia T, Choi YG, Yousefzadeh MJ, Robbins PD, Mitchell JR, Acar M, Sarnoski EA, Bene MR, Salmon A, Kumar N, Miller RA. Harrison DE, et al. Among authors: allsopp r. Geroscience. 2024 Feb;46(1):795-816. doi: 10.1007/s11357-023-01011-0. Epub 2023 Dec 2. Geroscience. 2024. PMID: 38041783 Free PMC article.
Circulating microRNA profile of long-lived Okinawans identifies novel potential targets for optimizing lifespan and health span.
Noureddine S, Schneider A, Strader S, Zhu X, Dhahbi J, Allsopp R, Willcox DC, Donlon TA, Shimabukuro M, Higa M, Suzuki M, Torigoe T, Ashiqueali S, Yadav H, Willcox BJ, Masternak MM. Noureddine S, et al. Among authors: allsopp r. Aging Cell. 2024 Aug;23(8):e14191. doi: 10.1111/acel.14191. Epub 2024 May 15. Aging Cell. 2024. PMID: 38751007 Free PMC article.
122 results