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Page 1
Astaxanthin and meclizine extend lifespan in UM-HET3 male mice; fisetin, SG1002 (hydrogen sulfide donor), dimethyl fumarate, mycophenolic acid, and 4-phenylbutyrate do not significantly affect lifespan in either sex at the doses and schedules used.
Harrison DE, Strong R, Reifsnyder P, Rosenthal N, Korstanje R, Fernandez E, Flurkey K, Ginsburg BC, Murrell MD, Javors MA, Lopez-Cruzan M, Nelson JF, Willcox BJ, Allsopp R, Watumull DM, Watumull DG, Cortopassi G, Kirkland JL, Tchkonia T, Choi YG, Yousefzadeh MJ, Robbins PD, Mitchell JR, Acar M, Sarnoski EA, Bene MR, Salmon A, Kumar N, Miller RA. Harrison DE, et al. Among authors: robbins pd. Geroscience. 2024 Feb;46(1):795-816. doi: 10.1007/s11357-023-01011-0. Epub 2023 Dec 2. Geroscience. 2024. PMID: 38041783 Free PMC article.
In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers.
Samakkarnthai P, Saul D, Zhang L, Aversa Z, Doolittle ML, Sfeir JG, Kaur J, Atkinson EJ, Edwards JR, Russell GG, Pignolo RJ, Kirkland JL, Tchkonia T, Niedernhofer LJ, Monroe DG, Lebrasseur NK, Farr JN, Robbins PD, Khosla S. Samakkarnthai P, et al. Among authors: robbins pd. Aging (Albany NY). 2023 May 7;15(9):3331-3355. doi: 10.18632/aging.204701. Epub 2023 May 7. Aging (Albany NY). 2023. PMID: 37154858 Free PMC article.
Local senolysis in aged mice only partially replicates the benefits of systemic senolysis.
Farr JN, Saul D, Doolittle ML, Kaur J, Rowsey JL, Vos SJ, Froemming MN, Lagnado AB, Zhu Y, Weivoda M, Ikeno Y, Pignolo RJ, Niedernhofer LJ, Robbins PD, Jurk D, Passos JF, LeBrasseur NK, Tchkonia T, Kirkland JL, Monroe DG, Khosla S. Farr JN, et al. Among authors: robbins pd. J Clin Invest. 2023 Apr 17;133(8):e162519. doi: 10.1172/JCI162519. J Clin Invest. 2023. PMID: 36809340 Free PMC article.
Failure to repair endogenous DNA damage in β-cells causes adult-onset diabetes in mice.
Yousefzadeh MJ, Huerta Guevara AP, Postmus AC, Flores RR, Sano T, Jurdzinski A, Angelini L, McGowan SJ, O'Kelly RD, Wade EA, Gonzalez-Espada LV, Henessy-Wack D, Howard S, Rozgaja TA, Trussoni CE, LaRusso NF, Eggen BJL, Jonker JW, Robbins PD, Niedernhofer LJ, Kruit JK. Yousefzadeh MJ, et al. Among authors: robbins pd. Aging Biol. 2023;1(1):20230015. doi: 10.59368/agingbio.20230015. Epub 2023 Oct 23. Aging Biol. 2023. PMID: 38124711 Free PMC article.
Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity.
Lyu YX, Fu Q, Wilczok D, Ying K, King A, Antebi A, Vojta A, Stolzing A, Moskalev A, Georgievskaya A, Maier AB, Olsen A, Groth A, Simon AK, Brunet A, Jamil A, Kulaga A, Bhatti A, Yaden B, Pedersen BK, Schumacher B, Djordjevic B, Kennedy B, Chen C, Huang CY, Correll CU, Murphy CT, Ewald CY, Chen D, Valenzano DR, Sołdacki D, Erritzoe D, Meyer D, Sinclair DA, Chini EN, Teeling EC, Morgen E, Verdin E, Vernet E, Pinilla E, Fang EF, Bischof E, Mercken EM, Finger F, Kuipers F, Pun FW, Gyülveszi G, Civiletto G, Zmudze G, Blander G, Pincus HA, McClure J, Kirkland JL, Peyer J, Justice JN, Vijg J, Gruhn JR, McLaughlin J, Mannick J, Passos J, Baur JA, Betts-LaCroix J, Sedivy JM, Speakman JR, Shlain J, von Maltzahn J, Andreasson KI, Moody K, Palikaras K, Fortney K, Niedernhofer LJ, Rasmussen LJ, Veenhoff LM, Melton L, Ferrucci L, Quarta M, Koval M, Marinova M, Hamalainen M, Unfried M, Ringel MS, Filipovic M, Topors M, Mitin N, Roy N, Pintar N, Barzilai N, Binetti P, Singh P, Kohlhaas P, Robbins PD, Rubin P, Fedichev PO, Kamya P, Muñoz-Canoves P, de Cabo R, Faragher RGA, Konrad R, Ripa R, Mansukhani R, Büttner S, Wickström SA, Brunemeier S, Jakimov S, Luo S, Rosenzweig-Lipson S, Tsai SY, … See abstract for full author list ➔ Lyu YX, et al. Among authors: robbins pd. Aging (Albany NY). 2024 Oct 16;16(20):12955-12976. doi: 10.18632/aging.206135. Epub 2024 Oct 16. Aging (Albany NY). 2024. PMID: 39418098 Free PMC article. Review.
Osteoarthritis gene therapy in 2022.
Evans CH, Ghivizzani SC, Robbins PD. Evans CH, et al. Among authors: robbins pd. Curr Opin Rheumatol. 2023 Jan 1;35(1):37-43. doi: 10.1097/BOR.0000000000000918. Epub 2022 Nov 9. Curr Opin Rheumatol. 2023. PMID: 36508307 Free PMC article. Review.
The Fourth Annual Symposium of the Midwest Aging Consortium.
Kim J, Buffenstein R, Bronikowski AM, Pilar Vanegas ND, Rosas L, Agudelo-Garcia P, Mora AL, Rojas M, Englund DA, LeBrasseur NK, Nunes A, Robbins PD, Kohut ML, Kothadiya S, Bardhan R, Camell CD, Sturmlechner I, Goronzy JJ, Yeh CY, Lamming DW, Huang S, Leiser SF, Escorcia W, Gill MS, Taylor JR, Helfand SL, Korm S, Gribble KE, Pehar M, Blaszkiewicz M, Townsend KL, McGregor ER, Anderson RM, Stilgenbauer L, Sadagurski M, Taylor A, McNeill E, Stoeger T, Bai H. Kim J, et al. Among authors: robbins pd. J Gerontol A Biol Sci Med Sci. 2024 Nov 1;79(11):glae236. doi: 10.1093/gerona/glae236. J Gerontol A Biol Sci Med Sci. 2024. PMID: 39498863 Free PMC article.
The Fifth Annual Symposium of the Midwest Aging Consortium.
Reader BF, Rosas L, Knopf BA, Liu Y, Alzate-Correa D, Bhat A, Carey A, Cuervo AM, Dayal S, Demarco RS, Elliehausen CJ, Englund DA, Hamilton HL, Johnston M, Kang P, Konopka AR, Lepola N, Presley CJ, Schafer MJ, Serrano J, Singer BD, Song MA, Stanford KI, Taylor J, Wei W, Yeh CY, Zhang L, Zhang L, Anderson RM, Bai H, Robbins PD, Lamming DW, Mihaylova MM, Rojas M, Mora AL. Reader BF, et al. Among authors: robbins pd. J Gerontol A Biol Sci Med Sci. 2024 Dec 20:glae296. doi: 10.1093/gerona/glae296. Online ahead of print. J Gerontol A Biol Sci Med Sci. 2024. PMID: 39704343
542 results