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The Pgb1 locus controls glycogen aggregation in astrocytes of the aged hippocampus without impacting cognitive function.
Gómez-Pascual A, Glikman DM, Ng HX, Tomkins JE, Lu L, Xu Y, Ashbrook DG, Kaczorowski C, Kempermann G, Killmar J, Mozhui K, Ohlenschläger O, Aebersold R, Ingram DK, Williams EG, Williams RW, Overall RW, Jucker M, de Bakker DEM. Gómez-Pascual A, et al. Among authors: jucker m. bioRxiv [Preprint]. 2024 Jul 8:2023.11.22.567373. doi: 10.1101/2023.11.22.567373. bioRxiv. 2024. PMID: 38045339 Free PMC article. Preprint.
Increasing hub disruption parallels dementia severity in autosomal dominant Alzheimer disease.
Tu JC, Millar PR, Strain JF, Eck A, Adeyemo B, Daniels A, Karch C, Huey ED, McDade E, Day GS, Yakushev I, Hassenstab J, Morris J, Llibre-Guerra JJ, Ibanez L, Jucker M, Mendez PC, Bateman RJ, Perrin RJ, Benzinger T, Jack CR Jr, Betzel R, Ances BM, Eggebrecht AT, Gordon BA, Wheelock MD; Dominantly Inherited Alzheimer Network. Tu JC, et al. Among authors: jucker m. bioRxiv [Preprint]. 2023 Nov 1:2023.10.29.564633. doi: 10.1101/2023.10.29.564633. bioRxiv. 2023. Update in: Netw Neurosci. 2024 Dec 10;8(4):1265-1290. doi: 10.1162/netn_a_00395 PMID: 37961586 Free PMC article. Updated. Preprint.
Laminins in the adult and aged brain.
Jucker M, Tian M, Ingram DK. Jucker M, et al. Mol Chem Neuropathol. 1996 May-Aug;28(1-3):209-18. doi: 10.1007/BF02815224. Mol Chem Neuropathol. 1996. PMID: 8871961 Review.
Experimental evidence for temporal uncoupling of brain Aβ deposition and neurodegenerative sequelae.
Rother C, Uhlmann RE, Müller SA, Schelle J, Skodras A, Obermüller U, Häsler LM, Lambert M, Baumann F, Xu Y, Bergmann C, Salvadori G, Loos M, Brzak I, Shimshek D, Neumann U; Dominantly Inherited Alzheimer Network; Walker LC, Schultz SA, Chhatwal JP, Kaeser SA, Lichtenthaler SF, Staufenbiel M, Jucker M. Rother C, et al. Among authors: jucker m. Nat Commun. 2022 Nov 28;13(1):7333. doi: 10.1038/s41467-022-34538-5. Nat Commun. 2022. PMID: 36443293 Free PMC article.
Medin aggregation causes cerebrovascular dysfunction in aging wild-type mice.
Degenhardt K, Wagner J, Skodras A, Candlish M, Koppelmann AJ, Wild K, Maxwell R, Rotermund C, von Zweydorf F, Gloeckner CJ, Davies HA, Madine J, Del Turco D, Feederle R, Lashley T, Deller T, Kahle P, Hefendehl JK, Jucker M, Neher JJ. Degenhardt K, et al. Among authors: jucker m. Proc Natl Acad Sci U S A. 2020 Sep 22;117(38):23925-23931. doi: 10.1073/pnas.2011133117. Epub 2020 Sep 8. Proc Natl Acad Sci U S A. 2020. PMID: 32900929 Free PMC article.
373 results