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PolySialic acid-nanoparticles inhibit macrophage mediated inflammation through Siglec agonism: a potential treatment for age related macular degeneration.
Krishnan A, Sendra VG, Patel D, Lad A, Greene MK, Smyth P, Gallaher SA, Herron ÚM, Scott CJ, Genead M, Tolentino M. Krishnan A, et al. Among authors: scott cj. Front Immunol. 2023 Nov 16;14:1237016. doi: 10.3389/fimmu.2023.1237016. eCollection 2023. Front Immunol. 2023. PMID: 38045700 Free PMC article.
Nanoencapsulation of ABT-737 and camptothecin enhances their clinical potential through synergistic antitumor effects and reduction of systemic toxicity.
Schmid D, Jarvis GE, Fay F, Small DM, Greene MK, Majkut J, Spence S, McLaughlin KM, McCloskey KD, Johnston PG, Kissenpfennig A, Longley DB, Scott CJ. Schmid D, et al. Among authors: scott cj. Cell Death Dis. 2014 Oct 9;5(10):e1454. doi: 10.1038/cddis.2014.413. Cell Death Dis. 2014. PMID: 25299779 Free PMC article.
Targeting Siglecs with a sialic acid-decorated nanoparticle abrogates inflammation.
Spence S, Greene MK, Fay F, Hams E, Saunders SP, Hamid U, Fitzgerald M, Beck J, Bains BK, Smyth P, Themistou E, Small DM, Schmid D, O'Kane CM, Fitzgerald DC, Abdelghany SM, Johnston JA, Fallon PG, Burrows JF, McAuley DF, Kissenpfennig A, Scott CJ. Spence S, et al. Among authors: scott cj. Sci Transl Med. 2015 Sep 2;7(303):303ra140. doi: 10.1126/scitranslmed.aab3459. Sci Transl Med. 2015. PMID: 26333936
Alum Activates the Bovine NLRP3 Inflammasome.
Harte C, Gorman AL, McCluskey S, Carty M, Bowie AG, Scott CJ, Meade KG, Lavelle EC. Harte C, et al. Among authors: scott cj. Front Immunol. 2017 Nov 9;8:1494. doi: 10.3389/fimmu.2017.01494. eCollection 2017. Front Immunol. 2017. PMID: 29209310 Free PMC article.
307 results