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The allosteric dopamine D1 receptor potentiator, DETQ, ameliorates subchronic phencyclidine-induced object recognition memory deficits and enhances cortical acetylcholine efflux in male humanized D1 receptor knock-in mice.
Meltzer HY, Rajagopal L, Matrisciano F, Hao J, Svensson KA, Huang M. Meltzer HY, et al. Among authors: huang m. Behav Brain Res. 2019 Apr 1;361:139-150. doi: 10.1016/j.bbr.2018.12.006. Epub 2018 Dec 3. Behav Brain Res. 2019. PMID: 30521930
NU-1223, a simplified analog of alstonine, with 5-HT2cR agonist-like activity, rescues memory deficit and positive and negative symptoms in subchronic phencyclidine mouse model of schizophrenia.
Rajagopal L, Mahjour S, Huang M, Ryan CA, Elzokaky A, Csakai AJ, Orr MJ, Scheidt K, Meltzer HY. Rajagopal L, et al. Among authors: huang m. Behav Brain Res. 2023 Oct 2;454:114614. doi: 10.1016/j.bbr.2023.114614. Epub 2023 Aug 10. Behav Brain Res. 2023. PMID: 37572758
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