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Platelets interact with CD169+ macrophages and cDC1 and enhance liposome-induced CD8+ T cell responses.
Grabowska J, Léopold V, Olesek K, Nijen Twilhaar MK, Affandi AJ, Brouwer MC, Jongerius I, Verschoor A, van Kooten C, van Kooyk Y, Storm G, van 't Veer C, den Haan JMM. Grabowska J, et al. Among authors: affandi aj. Front Immunol. 2023 Nov 20;14:1290272. doi: 10.3389/fimmu.2023.1290272. eCollection 2023. Front Immunol. 2023. PMID: 38054006 Free PMC article.
Spatial immune composition of tumor microenvironment in patients with pancreatic cancer.
Zwart ES, van Ee T, Affandi AJ, Boyd LNC, Rodriguez E, den Haan JMM, Farina A, van Grieken NCT, Meijer LL, van Kooyk Y, Mebius RE, Kazemier G. Zwart ES, et al. Among authors: affandi aj. Cancer Immunol Immunother. 2023 Dec;72(12):4385-4397. doi: 10.1007/s00262-023-03573-6. Epub 2023 Nov 8. Cancer Immunol Immunother. 2023. PMID: 37938368 Free PMC article.
Nanobody-liposomes as novel cancer vaccine platform to efficiently stimulate T cell immunity.
Bouma RG, Nijen Twilhaar MK, Brink HJ, Affandi AJ, Mesquita BS, Olesek K, van Dommelen JMA, Heukers R, de Haas AM, Kalay H, Ambrosini M, Metselaar JM, van Rooijen A, Storm G, Oliveira S, van Kooyk Y, den Haan JMM. Bouma RG, et al. Among authors: affandi aj. Int J Pharm. 2024 Jul 20;660:124254. doi: 10.1016/j.ijpharm.2024.124254. Epub 2024 May 23. Int J Pharm. 2024. PMID: 38795934 Free article.
Development of a Versatile Cancer Vaccine Format Targeting Antigen-Presenting Cells Using Proximity-Based Sortase A-Mediated Ligation of T-Cell Epitopes.
Wang AZ, Brink HJ, Bouma RG, Affandi AJ, Nijen Twilhaar MK, Heijnen DAM, van Elk J, Maaskant JJ, Konijn VAL, Stolwijk JGC, Kalay H, Olesek K, van Kooyk Y, van der Schoot JMS, Bentlage AEH, Scheeren FA, Verdoes M, Vidarsson G, Kuijl CP, den Haan JMM. Wang AZ, et al. Among authors: affandi aj. Bioconjug Chem. 2024 Nov 20;35(11):1805-1814. doi: 10.1021/acs.bioconjchem.4c00403. Epub 2024 Nov 7. Bioconjug Chem. 2024. PMID: 39511711 Free PMC article.
Impaired LAIR-1-mediated immune control due to collagen degradation in fibrosis.
Carvalheiro T, Marut W, Pascoal Ramos MI, García S, Fleury D, Affandi AJ, Meijers AS, Giovannone B, Tieland RG, Elshof E, Ottria A, Cossu M, Meizlish ML, Veenendaal T, Ramanujam M, Moreno-García ME, Klumperman J, Liv N, Radstake TRDJ, Meyaard L. Carvalheiro T, et al. Among authors: affandi aj. J Autoimmun. 2024 Jun;146:103219. doi: 10.1016/j.jaut.2024.103219. Epub 2024 May 1. J Autoimmun. 2024. PMID: 38696927 Free article.
An Organotypic Human Lymph Node Model Reveals the Importance of Fibroblastic Reticular Cells for Dendritic Cell Function.
Morrison AI, Mikula AM, Spiekstra SW, de Kok M, Affandi AJ, Roest HP, van der Laan LJW, de Winde CM, Koning JJ, Gibbs S, Mebius RE. Morrison AI, et al. Among authors: affandi aj. Tissue Eng Regen Med. 2024 Apr;21(3):455-471. doi: 10.1007/s13770-023-00609-x. Epub 2023 Dec 19. Tissue Eng Regen Med. 2024. PMID: 38114886 Free PMC article.
Nuclear Receptor Subfamily 4A Signaling as a Key Disease Pathway of CD1c+ Dendritic Cell Dysregulation in Systemic Sclerosis.
Servaas NH, Hiddingh S, Chouri E, Wichers CGK, Affandi AJ, Ottria A, Bekker CPJ, Cossu M, Silva-Cardoso SC, van der Kroef M, Hinrichs AC, Carvalheiro T, Vazirpanah N, Beretta L, Rossato M, Bonte-Mineur F, Radstake TRDJ, Kuiper JJW, Boes M, Pandit A. Servaas NH, et al. Among authors: affandi aj. Arthritis Rheumatol. 2023 Feb;75(2):279-292. doi: 10.1002/art.42319. Epub 2022 Dec 8. Arthritis Rheumatol. 2023. PMID: 36482877 Free PMC article.
Incorporation of Toll-Like Receptor Ligands and Inflammasome Stimuli in GM3 Liposomes to Induce Dendritic Cell Maturation and T Cell Responses.
Nijen Twilhaar MK, Czentner L, Bouma RG, Olesek K, Grabowska J, Wang AZ, Affandi AJ, Belt SC, Kalay H, van Nostrum CF, van Kooyk Y, Storm G, den Haan JMM. Nijen Twilhaar MK, et al. Among authors: affandi aj. Front Immunol. 2022 Feb 18;13:842241. doi: 10.3389/fimmu.2022.842241. eCollection 2022. Front Immunol. 2022. PMID: 35251040 Free PMC article.
CXCL4 drives fibrosis by promoting several key cellular and molecular processes.
Affandi AJ, Carvalheiro T, Ottria A, de Haan JJ, Brans MAD, Brandt MM, Tieland RG, Lopes AP, Fernández BM, Bekker CPJ, van der Linden M, Zimmermann M, Giovannone B, Wichers CGK, Garcia S, de Kok M, Stifano G, Xu YJ, Kowalska MA, Waasdorp M, Cheng C, Gibbs S, de Jager SCA, van Roon JAG, Radstake TRDJ, Marut W. Affandi AJ, et al. Cell Rep. 2022 Jan 4;38(1):110189. doi: 10.1016/j.celrep.2021.110189. Cell Rep. 2022. PMID: 34986347 Free article.
36 results