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In silico ADMET prediction, evaluation of cytotoxicity in mouse splenocytes and preliminary evaluation of in vitro antimalarial activity of 4-(4-chlorophenyl)thiazole compounds.
Silva BRMGD, Bezerra Júnior NDS, Oliveira JF, Duarte DMFA, Marques DSC, Nogueira F, Lima MCA, Cruz Filho IJD. Silva BRMGD, et al. Among authors: cruz filho ijd. An Acad Bras Cienc. 2023 Dec 4;95(suppl 2):e20230566. doi: 10.1590/0001-3765202320230566. eCollection 2023. An Acad Bras Cienc. 2023. PMID: 38055446 Free article.
Saline extract from Malpighia emarginata DC leaves showed higher polyphenol presence, antioxidant and antifungal activity and promoted cell proliferation in mice splenocytes.
Barros BRS, Barboza BR, Ramos BA, Moura MC, Coelho LCBB, Napoleão TH, Correia MTS, Paiva PMG, Cruz Filho IJD, Silva TDD, Lima CSA, Melo CML. Barros BRS, et al. An Acad Bras Cienc. 2019;91(1):e20190916. doi: 10.1590/0001-3765201920180358. Epub 2019 Apr 8. An Acad Bras Cienc. 2019. PMID: 30994765 Free article.
Plumbagin: A Promising In Vivo Antiparasitic Candidate against Schistosoma mansoni and In Silico Pharmacokinetic Properties (ADMET).
Silva LMN, França WWM, Santos VHB, Souza RAF, Silva AM, Diniz EGM, Aguiar TWA, Rocha JVR, Souza MAA, Nascimento WRC, Lima Neto RG, Cruz Filho IJ, Ximenes ECPA, Araújo HDA, Aires AL, Albuquerque MCPA. Silva LMN, et al. Among authors: cruz filho ij. Biomedicines. 2023 Aug 22;11(9):2340. doi: 10.3390/biomedicines11092340. Biomedicines. 2023. PMID: 37760782 Free PMC article.
Xylan from Dinizia excelsa: Chemical characterization and biological activities.
Oliveira IM, Leite SP, Mesquita ARC, Araújo HDA, Aires AL, Marques DSC, Lima MCA, Cruz Filho IJ. Oliveira IM, et al. Among authors: cruz filho ij. An Acad Bras Cienc. 2024 Nov 29;96(suppl 3):e20240219. doi: 10.1590/0001-3765202420240219. eCollection 2024. An Acad Bras Cienc. 2024. PMID: 39630801 Free article.
5-nitro-thiophene-thiosemicarbazone derivative induces cell death, cell cycle arrest, and phospho-kinase shutdown in pancreatic ductal adenocarcinoma cells.
Costa VCMD, Lima MDCA, da Cruz Filho IJ, Galdino LV, Pereira MC, Silva BO, Albuquerque APB, da Rosa MM, Pitta MGDR, Rêgo MJBM. Costa VCMD, et al. Among authors: da cruz filho ij. Eur J Pharmacol. 2024 Nov 15;983:176963. doi: 10.1016/j.ejphar.2024.176963. Epub 2024 Sep 12. Eur J Pharmacol. 2024. PMID: 39260813
Therapeutic potential of hydantoin and thiohydantoin compounds against Schistosoma mansoni: An integrated in vitro, DNA, ultrastructural, and ADMET in silico approach.
Almeida Júnior AS, Freitas Viana Leal MM, Marques DSC, Silva ALD, Souza Bezerra R, Siqueira de Souza YF, Mendonça Silveira ME, Santos FA, Alves LC, de Lima Aires A, Cruz Filho IJD, do Carmo Alves de Lima M. Almeida Júnior AS, et al. Among authors: cruz filho ijd. Mol Biochem Parasitol. 2024 Dec;260:111646. doi: 10.1016/j.molbiopara.2024.111646. Epub 2024 Jun 29. Mol Biochem Parasitol. 2024. PMID: 38950658
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