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RAD54L2 counters TOP2-DNA adducts to promote genome stability.
D'Alessandro G, Morales-Juarez DA, Richards SL, Nitiss KC, Serrano-Benitez A, Wang J, Thomas JC, Gupta V, Voigt A, Belotserkovskaya R, Goh CG, Bowden AR, Galanty Y, Beli P, Nitiss JL, Zagnoli-Vieira G, Jackson SP. D'Alessandro G, et al. Sci Adv. 2023 Dec 8;9(49):eadl2108. doi: 10.1126/sciadv.adl2108. Epub 2023 Dec 6. Sci Adv. 2023. PMID: 38055822 Free PMC article.
Transcription-coupled repair of DNA-protein cross-links depends on CSA and CSB.
Carnie CJ, Acampora AC, Bader AS, Erdenebat C, Zhao S, Bitensky E, van den Heuvel D, Parnas A, Gupta V, D'Alessandro G, Sczaniecka-Clift M, Weickert P, Aygenli F, Götz MJ, Cordes J, Esain-Garcia I, Melidis L, Wondergem AP, Lam S, Robles MS, Balasubramanian S, Adar S, Luijsterburg MS, Jackson SP, Stingele J. Carnie CJ, et al. Nat Cell Biol. 2024 May;26(5):797-810. doi: 10.1038/s41556-024-01391-1. Epub 2024 Apr 10. Nat Cell Biol. 2024. PMID: 38600235 Free PMC article.
Decitabine cytotoxicity is promoted by dCMP deaminase DCTD and mitigated by SUMO-dependent E3 ligase TOPORS.
Carnie CJ, Götz MJ, Palma-Chaundler CS, Weickert P, Wanders A, Serrano-Benitez A, Li HY, Gupta V, Awwad SW, Blum CJ, Sczaniecka-Clift M, Cordes J, Zagnoli-Vieira G, D'Alessandro G, Richards SL, Gueorguieva N, Lam S, Beli P, Stingele J, Jackson SP. Carnie CJ, et al. Among authors: d alessandro g. EMBO J. 2024 Jun;43(12):2397-2423. doi: 10.1038/s44318-024-00108-2. Epub 2024 May 17. EMBO J. 2024. PMID: 38760575 Free PMC article.
USP37 prevents premature disassembly of stressed replisomes by TRAIP.
Kochenova OV, D'Alessandro G, Pilger D, Schmid E, Richards SL, Garcia MR, Jhujh SS, Voigt A, Gupta V, Carnie CJ, Wu RA, Gueorguieva N, Stewart GS, Walter JC, Jackson SP. Kochenova OV, et al. Among authors: d alessandro g. bioRxiv [Preprint]. 2024 Sep 4:2024.09.03.611025. doi: 10.1101/2024.09.03.611025. bioRxiv. 2024. PMID: 39282314 Free PMC article. Preprint.
Microglia in Glioma.
Garofalo S, D'Alessandro G, Limatola C. Garofalo S, et al. Among authors: d alessandro g. Adv Neurobiol. 2024;37:513-527. doi: 10.1007/978-3-031-55529-9_28. Adv Neurobiol. 2024. PMID: 39207710 Review.
BV2-derived extracellular vesicles modulate microglia inflammatory profile, neuronal plasticity, and behavioural performances in late adult mice.
Rinaldi A, Balietti M, Principi E, De Luca M, De Felice E, Narcisi FM, Vilardo L, Rosito M, Piacentini R, D'Alessandro G, D'Agnano I, Maggi L, Conti F, Limatola C, Catalano M. Rinaldi A, et al. Among authors: d alessandro g. Brain Behav Immun. 2024 Nov;122:58-74. doi: 10.1016/j.bbi.2024.08.012. Epub 2024 Aug 10. Brain Behav Immun. 2024. PMID: 39128568
321 results