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RAD54L2 counters TOP2-DNA adducts to promote genome stability.
D'Alessandro G, Morales-Juarez DA, Richards SL, Nitiss KC, Serrano-Benitez A, Wang J, Thomas JC, Gupta V, Voigt A, Belotserkovskaya R, Goh CG, Bowden AR, Galanty Y, Beli P, Nitiss JL, Zagnoli-Vieira G, Jackson SP. D'Alessandro G, et al. Among authors: galanty y. Sci Adv. 2023 Dec 8;9(49):eadl2108. doi: 10.1126/sciadv.adl2108. Epub 2023 Dec 6. Sci Adv. 2023. PMID: 38055822 Free PMC article.
CtIP tetramer assembly is required for DNA-end resection and repair.
Davies OR, Forment JV, Sun M, Belotserkovskaya R, Coates J, Galanty Y, Demir M, Morton CR, Rzechorzek NJ, Jackson SP, Pellegrini L. Davies OR, et al. Among authors: galanty y. Nat Struct Mol Biol. 2015 Feb;22(2):150-157. doi: 10.1038/nsmb.2937. Epub 2015 Jan 5. Nat Struct Mol Biol. 2015. PMID: 25558984 Free PMC article.
Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites.
Brown JS, Lukashchuk N, Sczaniecka-Clift M, Britton S, le Sage C, Calsou P, Beli P, Galanty Y, Jackson SP. Brown JS, et al. Among authors: galanty y. Cell Rep. 2015 May 5;11(5):704-14. doi: 10.1016/j.celrep.2015.03.058. Epub 2015 Apr 23. Cell Rep. 2015. PMID: 25921528 Free PMC article.
Systematic E2 screening reveals a UBE2D-RNF138-CtIP axis promoting DNA repair.
Schmidt CK, Galanty Y, Sczaniecka-Clift M, Coates J, Jhujh S, Demir M, Cornwell M, Beli P, Jackson SP. Schmidt CK, et al. Among authors: galanty y. Nat Cell Biol. 2015 Nov;17(11):1458-1470. doi: 10.1038/ncb3260. Epub 2015 Oct 26. Nat Cell Biol. 2015. PMID: 26502057 Free PMC article.
Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells.
Dev H, Chiang TW, Lescale C, de Krijger I, Martin AG, Pilger D, Coates J, Sczaniecka-Clift M, Wei W, Ostermaier M, Herzog M, Lam J, Shea A, Demir M, Wu Q, Yang F, Fu B, Lai Z, Balmus G, Belotserkovskaya R, Serra V, O'Connor MJ, Bruna A, Beli P, Pellegrini L, Caldas C, Deriano L, Jacobs JJL, Galanty Y, Jackson SP. Dev H, et al. Among authors: galanty y. Nat Cell Biol. 2018 Aug;20(8):954-965. doi: 10.1038/s41556-018-0140-1. Epub 2018 Jul 18. Nat Cell Biol. 2018. PMID: 30022119 Free PMC article.
27 results