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Page 1
RAD54L2 counters TOP2-DNA adducts to promote genome stability.
D'Alessandro G, Morales-Juarez DA, Richards SL, Nitiss KC, Serrano-Benitez A, Wang J, Thomas JC, Gupta V, Voigt A, Belotserkovskaya R, Goh CG, Bowden AR, Galanty Y, Beli P, Nitiss JL, Zagnoli-Vieira G, Jackson SP. D'Alessandro G, et al. Among authors: zagnoli vieira g. Sci Adv. 2023 Dec 8;9(49):eadl2108. doi: 10.1126/sciadv.adl2108. Epub 2023 Dec 6. Sci Adv. 2023. PMID: 38055822 Free PMC article.
Combinatorial CRISPR screen identifies fitness effects of gene paralogues.
Thompson NA, Ranzani M, van der Weyden L, Iyer V, Offord V, Droop A, Behan F, Gonçalves E, Speak A, Iorio F, Hewinson J, Harle V, Robertson H, Anderson E, Fu B, Yang F, Zagnoli-Vieira G, Chapman P, Del Castillo Velasco-Herrera M, Garnett MJ, Jackson SP, Adams DJ. Thompson NA, et al. Among authors: zagnoli vieira g. Nat Commun. 2021 Feb 26;12(1):1302. doi: 10.1038/s41467-021-21478-9. Nat Commun. 2021. PMID: 33637726 Free PMC article.
Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity.
Canela A, Maman Y, Huang SN, Wutz G, Tang W, Zagnoli-Vieira G, Callen E, Wong N, Day A, Peters JM, Caldecott KW, Pommier Y, Nussenzweig A. Canela A, et al. Among authors: zagnoli vieira g. Mol Cell. 2019 Jul 25;75(2):252-266.e8. doi: 10.1016/j.molcel.2019.04.030. Epub 2019 Jun 12. Mol Cell. 2019. PMID: 31202577 Free PMC article.
TDP2, TOP2, and SUMO: what is ZATT about?
Zagnoli-Vieira G, Caldecott KW. Zagnoli-Vieira G, et al. Cell Res. 2017 Dec;27(12):1405-1406. doi: 10.1038/cr.2017.147. Epub 2017 Nov 21. Cell Res. 2017. PMID: 29160298 Free PMC article.
Decitabine cytotoxicity is promoted by dCMP deaminase DCTD and mitigated by SUMO-dependent E3 ligase TOPORS.
Carnie CJ, Götz MJ, Palma-Chaundler CS, Weickert P, Wanders A, Serrano-Benitez A, Li HY, Gupta V, Awwad SW, Blum CJ, Sczaniecka-Clift M, Cordes J, Zagnoli-Vieira G, D'Alessandro G, Richards SL, Gueorguieva N, Lam S, Beli P, Stingele J, Jackson SP. Carnie CJ, et al. Among authors: zagnoli vieira g. EMBO J. 2024 Jun;43(12):2397-2423. doi: 10.1038/s44318-024-00108-2. Epub 2024 May 17. EMBO J. 2024. PMID: 38760575 Free PMC article.
Large-scale exome sequence analysis identifies sex- and age-specific determinants of obesity.
Kaisinger LR, Kentistou KA, Stankovic S, Gardner EJ, Day FR, Zhao Y, Mörseburg A, Carnie CJ, Zagnoli-Vieira G, Puddu F, Jackson SP, O'Rahilly S, Farooqi IS, Dearden L, Pantaleão LC, Ozanne SE, Ong KK, Perry JRB. Kaisinger LR, et al. Among authors: zagnoli vieira g. Cell Genom. 2023 Aug 2;3(8):100362. doi: 10.1016/j.xgen.2023.100362. eCollection 2023 Aug 9. Cell Genom. 2023. PMID: 37601970 Free PMC article.
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