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Page 1
Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion.
Matoba K, Kotani T, Tsutsumi A, Tsuji T, Mori T, Noshiro D, Sugita Y, Nomura N, Iwata S, Ohsumi Y, Fujimoto T, Nakatogawa H, Kikkawa M, Noda NN. Matoba K, et al. Among authors: noshiro d. Nat Struct Mol Biol. 2020 Dec;27(12):1185-1193. doi: 10.1038/s41594-020-00518-w. Epub 2020 Oct 26. Nat Struct Mol Biol. 2020. PMID: 33106658
Phase separation organizes the site of autophagosome formation.
Fujioka Y, Alam JM, Noshiro D, Mouri K, Ando T, Okada Y, May AI, Knorr RL, Suzuki K, Ohsumi Y, Noda NN. Fujioka Y, et al. Among authors: noshiro d. Nature. 2020 Feb;578(7794):301-305. doi: 10.1038/s41586-020-1977-6. Epub 2020 Feb 5. Nature. 2020. PMID: 32025038
p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response.
Kageyama S, Gudmundsson SR, Sou YS, Ichimura Y, Tamura N, Kazuno S, Ueno T, Miura Y, Noshiro D, Abe M, Mizushima T, Miura N, Okuda S, Motohashi H, Lee JA, Sakimura K, Ohe T, Noda NN, Waguri S, Eskelinen EL, Komatsu M. Kageyama S, et al. Among authors: noshiro d. Nat Commun. 2021 Jan 4;12(1):16. doi: 10.1038/s41467-020-20185-1. Nat Commun. 2021. PMID: 33397898 Free PMC article.
The mitochondrial intermembrane space protein mitofissin drives mitochondrial fission required for mitophagy.
Fukuda T, Furukawa K, Maruyama T, Yamashita SI, Noshiro D, Song C, Ogasawara Y, Okuyama K, Alam JM, Hayatsu M, Saigusa T, Inoue K, Ikeda K, Takai A, Chen L, Lahiri V, Okada Y, Shibata S, Murata K, Klionsky DJ, Noda NN, Kanki T. Fukuda T, et al. Among authors: noshiro d. Mol Cell. 2023 Jun 15;83(12):2045-2058.e9. doi: 10.1016/j.molcel.2023.04.022. Epub 2023 May 15. Mol Cell. 2023. PMID: 37192628 Free PMC article.
A glutamine sensor that directly activates TORC1.
Tanigawa M, Yamamoto K, Nagatoishi S, Nagata K, Noshiro D, Noda NN, Tsumoto K, Maeda T. Tanigawa M, et al. Among authors: noshiro d. Commun Biol. 2021 Sep 17;4(1):1093. doi: 10.1038/s42003-021-02625-w. Commun Biol. 2021. PMID: 34535752 Free PMC article.
24 results