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Engineered mini-G proteins block the internalization of cognate GPCRs and disrupt downstream intracellular signaling.
Sci Signal. 2024 Jul 2;17(843):eabq7038. doi: 10.1126/scisignal.abq7038. Epub 2024 Jul 2.
Sci Signal. 2024.
PMID: 38954638
Epigenetic and Metabolic Reprogramming of Fibroblasts in Crohn's Disease Strictures Reveals Histone Deacetylases as Therapeutic Targets.
Lewis A, Humphreys DT, Pan-Castillo B, Berti G, Felice C, Gordon H, Gadhok R, Nijhuis A, Mehta S S, Eleid L, Iqbal S, Armuzzi A, Minicozzi A, Giannoulatou E, ChinAleong J, Feakins R, Sagi-Kiss V, Barisic D, Koufaki MI, Bundy JG, Lindsay JO, Silver A.
Lewis A, et al. Among authors: eleid l.
J Crohns Colitis. 2024 Jun 3;18(6):895-907. doi: 10.1093/ecco-jcc/jjad209.
J Crohns Colitis. 2024.
PMID: 38069679
Free PMC article.
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Small-molecule Wnt inhibitors are a potential novel therapy for intestinal fibrosis in Crohns disease.
Lewis A, Sánchez S, Berti G, Pan-Castillo B, Nijhuis A, Mehta S, Eleid L, Gordon H, Gadhok R, Kimberley C, Minicozzi A, Chin-Aleong J, Feakins R, Kypta R, Lindsay JO, Silver A.
Lewis A, et al. Among authors: eleid l.
Clin Sci (Lond). 2022 Oct 14;136(19):1405-1423. doi: 10.1042/CS20210889.
Clin Sci (Lond). 2022.
PMID: 36156078
Free PMC article.
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Cancer immunotherapy: Challenges and limitations.
Taefehshokr S, Parhizkar A, Hayati S, Mousapour M, Mahmoudpour A, Eleid L, Rahmanpour D, Fattahi S, Shabani H, Taefehshokr N.
Taefehshokr S, et al. Among authors: eleid l.
Pathol Res Pract. 2022 Jan;229:153723. doi: 10.1016/j.prp.2021.153723. Epub 2021 Nov 28.
Pathol Res Pract. 2022.
PMID: 34952426
Review.
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