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Page 1
Epigenetic and Metabolic Reprogramming of Fibroblasts in Crohn's Disease Strictures Reveals Histone Deacetylases as Therapeutic Targets.
Lewis A, Humphreys DT, Pan-Castillo B, Berti G, Felice C, Gordon H, Gadhok R, Nijhuis A, Mehta S S, Eleid L, Iqbal S, Armuzzi A, Minicozzi A, Giannoulatou E, ChinAleong J, Feakins R, Sagi-Kiss V, Barisic D, Koufaki MI, Bundy JG, Lindsay JO, Silver A. Lewis A, et al. Among authors: lindsay jo. J Crohns Colitis. 2024 Jun 3;18(6):895-907. doi: 10.1093/ecco-jcc/jjad209. J Crohns Colitis. 2024. PMID: 38069679 Free PMC article.
Genome-Wide Methylation Profiling in 229 Patients With Crohn's Disease Requiring Intestinal Resection: Epigenetic Analysis of the Trial of Prevention of Post-operative Crohn's Disease (TOPPIC).
Ventham NT, Kennedy NA, Kalla R, Adams AT, Noble A, Ennis H; TOPPIC Study Group; IBD-BIOM Consortium; Mowat C, Dunlop MG, Satsangi J. Ventham NT, et al. Cell Mol Gastroenterol Hepatol. 2023;16(3):431-450. doi: 10.1016/j.jcmgh.2023.06.001. Epub 2023 Jun 17. Cell Mol Gastroenterol Hepatol. 2023. PMID: 37331566 Free PMC article. Clinical Trial.
Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study.
Kennedy NA, Heap GA, Green HD, Hamilton B, Bewshea C, Walker GJ, Thomas A, Nice R, Perry MH, Bouri S, Chanchlani N, Heerasing NM, Hendy P, Lin S, Gaya DR, Cummings JRF, Selinger CP, Lees CW, Hart AL, Parkes M, Sebastian S, Mansfield JC, Irving PM, Lindsay J, Russell RK, McDonald TJ, McGovern D, Goodhand JR, Ahmad T; UK Inflammatory Bowel Disease Pharmacogenetics Study Group. Kennedy NA, et al. Lancet Gastroenterol Hepatol. 2019 May;4(5):341-353. doi: 10.1016/S2468-1253(19)30012-3. Epub 2019 Feb 27. Lancet Gastroenterol Hepatol. 2019. PMID: 30824404
Impact of pain, fatigue and bowel incontinence on the quality of life of people living with inflammatory bowel disease: A UK cross-sectional survey.
Roukas C, Miller L, Cléirigh Büttner F, Hamborg T, Stagg I, Hart A, Gordeev VS, Lindsay JO, Norton C, Mihaylova B. Roukas C, et al. Among authors: lindsay jo. United European Gastroenterol J. 2024 Oct 19:10.1002/ueg2.12668. doi: 10.1002/ueg2.12668. Online ahead of print. United European Gastroenterol J. 2024. PMID: 39425758 Free PMC article.
Risankizumab versus Ustekinumab for Moderate-to-Severe Crohn's Disease.
Peyrin-Biroulet L, Chapman JC, Colombel JF, Caprioli F, D'Haens G, Ferrante M, Schreiber S, Atreya R, Danese S, Lindsay JO, Bossuyt P, Siegmund B, Irving PM, Panaccione R, Cao Q, Neimark E, Wallace K, Anschutz T, Kligys K, Duan WR, Pivorunas V, Huang X, Berg S, Shu L, Dubinsky M; SEQUENCE Study Group. Peyrin-Biroulet L, et al. Among authors: lindsay jo. N Engl J Med. 2024 Jul 18;391(3):213-223. doi: 10.1056/NEJMoa2314585. N Engl J Med. 2024. PMID: 39018531 Clinical Trial.
Recommendations for Broadening Eligibility Criteria in Inflammatory Bowel Disease Clinical Trials.
Siegel CA, Rai V, Outtier A, Vermeire S, Law CCW, Sands BE, Abdulhamid A, Gearry R, McGuire J, Lindsay JO, Panaccione R, Schweistein H, Dotan I, Scarallo L, Griffiths A, Dubinsky MC; International Organization for the Study of Inflammatory Bowel Disease (IOIBD). Siegel CA, et al. Among authors: lindsay jo. J Crohns Colitis. 2024 Jun 22:jjae097. doi: 10.1093/ecco-jcc/jjae097. Online ahead of print. J Crohns Colitis. 2024. PMID: 38908002
Single cell sequencing data identify distinct B cell and fibroblast populations in stricturing Crohn's disease.
Humphreys DT, Lewis A, Pan-Castillo B, Berti G, Mein C, Wozniak E, Gordon H, Gadhok R, Minicozzi A, ChinAleong J, Feakins R, Giannoulatou E, James LK, Stagg AJ, Lindsay JO, Silver A. Humphreys DT, et al. Among authors: lindsay jo. J Cell Mol Med. 2024 May;28(9):e18344. doi: 10.1111/jcmm.18344. J Cell Mol Med. 2024. PMID: 38685679 Free PMC article.
176 results