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Epigenetic and Metabolic Reprogramming of Fibroblasts in Crohn's Disease Strictures Reveals Histone Deacetylases as Therapeutic Targets.
Lewis A, Humphreys DT, Pan-Castillo B, Berti G, Felice C, Gordon H, Gadhok R, Nijhuis A, Mehta S S, Eleid L, Iqbal S, Armuzzi A, Minicozzi A, Giannoulatou E, ChinAleong J, Feakins R, Sagi-Kiss V, Barisic D, Koufaki MI, Bundy JG, Lindsay JO, Silver A. Lewis A, et al. Among authors: silver a. J Crohns Colitis. 2024 Jun 3;18(6):895-907. doi: 10.1093/ecco-jcc/jjad209. J Crohns Colitis. 2024. PMID: 38069679 Free PMC article.
Investigating iRHOM2-Associated Transcriptional Changes in Tylosis With Esophageal Cancer.
Murtough S, Babu D, Webb CM, Louis Dit Picard H, McGinty LA, Chao-Chu J, Pink R, Silver AR, Smart HL, Field JK, Woodland P, Risk JM, Blaydon DC, Pennington DJ, Kelsell DP. Murtough S, et al. Among authors: silver ar. Gastro Hep Adv. 2023 Dec 26;3(3):385-395. doi: 10.1016/j.gastha.2023.12.007. eCollection 2024. Gastro Hep Adv. 2023. PMID: 39131151 Free PMC article.
A blueprint for pursuing therapeutic interventions and early phase clinical trials in clonal haematopoiesis.
Haque T, Shastri A, Desai P, Xie Z, Hammond D, King Z, Kishtagari A, Madanat YF, Abaza Y, Silver AJ, Singh A, Borate UM, Heimlich JB, Slosky DA, Bolton KL, Patnaik MS, Bick AG, Verma AK, Jaiswal S, Steensma DP, Savona MR. Haque T, et al. Among authors: silver aj. Br J Haematol. 2024 Dec 9. doi: 10.1111/bjh.19925. Online ahead of print. Br J Haematol. 2024. PMID: 39653653 Review.
Germline genetics, disease, and exposure to medication influence longitudinal dynamics of clonal hematopoiesis.
Mack T, Pershad Y, Vlasschaert C, Bejan CA, Heimlich JB, Li Y, Mickels NA, Van Amburg JC, Ulloa J, Silver AJ, Luo LY, Jones A, Ferrell PB, Kishtagari A, Xu Y, Savona MR, Bick AG. Mack T, et al. Among authors: silver aj. Haematologica. 2024 Nov 14. doi: 10.3324/haematol.2024.286513. Online ahead of print. Haematologica. 2024. PMID: 39540221 Free article.
704 results