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Genome mining of metabolic gene clusters in the Rubiaceae family.
Correia de Lemos SM, Paschoal AR, Guyot R, Medema M, Domingues DS. Correia de Lemos SM, et al. Among authors: medema m. Comput Struct Biotechnol J. 2023 Nov 20;23:22-33. doi: 10.1016/j.csbj.2023.11.034. eCollection 2024 Dec. Comput Struct Biotechnol J. 2023. PMID: 38075396 Free PMC article.
Metabolome-guided genome mining of RiPP natural products.
Zdouc MM, van der Hooft JJJ, Medema MH. Zdouc MM, et al. Among authors: medema mh. Trends Pharmacol Sci. 2023 Aug;44(8):532-541. doi: 10.1016/j.tips.2023.06.004. Epub 2023 Jun 29. Trends Pharmacol Sci. 2023. PMID: 37391295 Review.
A widely distributed gene cluster compensates for uricase loss in hominids.
Liu Y, Jarman JB, Low YS, Augustijn HE, Huang S, Chen H, DeFeo ME, Sekiba K, Hou BH, Meng X, Weakley AM, Cabrera AV, Zhou Z, van Wezel G, Medema MH, Ganesan C, Pao AC, Gombar S, Dodd D. Liu Y, et al. Among authors: medema mh. Cell. 2023 Aug 3;186(16):3400-3413.e20. doi: 10.1016/j.cell.2023.06.010. Cell. 2023. PMID: 37541197 Free PMC article.
MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration.
Zdouc MM, Blin K, Louwen NLL, Navarro J, Loureiro C, Bader CD, Bailey CB, Barra L, Booth TJ, Bozhüyük KAJ, Cediel-Becerra JDD, Charlop-Powers Z, Chevrette MG, Chooi YH, D'Agostino PM, de Rond T, Del Pup E, Duncan KR, Gu W, Hanif N, Helfrich EJN, Jenner M, Katsuyama Y, Korenskaia A, Krug D, Libis V, Lund GA, Mantri S, Morgan KD, Owen C, Phan CS, Philmus B, Reitz ZL, Robinson SL, Singh KS, Teufel R, Tong Y, Tugizimana F, Ulanova D, Winter JM, Aguilar C, Akiyama DY, Al-Salihi SAA, Alanjary M, Alberti F, Aleti G, Alharthi SA, Rojo MYA, Arishi AA, Augustijn HE, Avalon NE, Avelar-Rivas JA, Axt KK, Barbieri HB, Barbosa JCJ, Barboza Segato LG, Barrett SE, Baunach M, Beemelmanns C, Beqaj D, Berger T, Bernaldo-Agüero J, Bettenbühl SM, Bielinski VA, Biermann F, Borges RM, Borriss R, Breitenbach M, Bretscher KM, Brigham MW, Buedenbender L, Bulcock BW, Cano-Prieto C, Capela J, Carrion VJ, Carter RS, Castelo-Branco R, Castro-Falcón G, Chagas FO, Charria-Girón E, Chaudhri AA, Chaudhry V, Choi H, Choi Y, Choupannejad R, Chromy J, Donahey MSC, Collemare J, Connolly JA, Creamer KE, Crüsemann M, Cruz AA, Cumsille A, Dallery JF, Damas-Ramos LC, Damiani T, de Kruijff M, Martín BD, Sala GD, Dillen J, D… See abstract for full author list ➔ Zdouc MM, et al. Among authors: medema mh. Nucleic Acids Res. 2025 Jan 6;53(D1):D678-D690. doi: 10.1093/nar/gkae1115. Nucleic Acids Res. 2025. PMID: 39657789 Free PMC article.
Pairing omics to decode the diversity of plant specialized metabolism.
Wolters FC, Del Pup E, Singh KS, Bouwmeester K, Schranz ME, van der Hooft JJJ, Medema MH. Wolters FC, et al. Among authors: medema mh. Curr Opin Plant Biol. 2024 Dec;82:102657. doi: 10.1016/j.pbi.2024.102657. Epub 2024 Nov 10. Curr Opin Plant Biol. 2024. PMID: 39527852 Free article. Review.
158 results