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Platelets of COVID-19 patients display mitochondrial dysfunction, oxidative stress, and energy metabolism failure compatible with cell death.
Léopold V, Chouchane O, Butler JM, Schuurman AR, Michels EHA, de Brabander J, Schomakers BV, van Weeghel M, Picavet-Havik DI, Grootemaat AE, Douma RA, Reijnders TDY, Klarenbeek AM, Appelman B; Amsterdam University Medical Center COVID-19 Biobank Study [email protected]; Wiersinga WJ, van der Wel NN, den Dunnen J, Houtkooper RH, Van't Veer C, van der Poll T; Amsterdam University Medical Center COVID-19 Biobank Study Group. Léopold V, et al. Among authors: van weeghel m, van der wel nn, van t veer c, van der poll t. Res Pract Thromb Haemost. 2023 Sep 28;7(7):102213. doi: 10.1016/j.rpth.2023.102213. eCollection 2023 Oct. Res Pract Thromb Haemost. 2023. PMID: 38077825 Free PMC article.
Distinct cellular immune profiles in the airways and blood of critically ill patients with COVID-19.
Saris A, Reijnders TDY, Nossent EJ, Schuurman AR, Verhoeff J, Asten SV, Bontkes H, Blok S, Duitman J, Bogaard HJ, Heunks L, Lutter R, van der Poll T, Garcia Vallejo JJ; ArtDECO consortium and the Amsterdam UMC COVID study group. Saris A, et al. Among authors: van der poll t. Thorax. 2021 Oct;76(10):1010-1019. doi: 10.1136/thoraxjnl-2020-216256. Epub 2021 Apr 12. Thorax. 2021. PMID: 33846275 Free PMC article.
Anti-C5a antibody vilobelimab treatment and the effect on biomarkers of inflammation and coagulation in patients with severe COVID-19: a substudy of the  phase 2 PANAMO trial.
Lim EHT, Vlaar APJ, Bos LDJ, van Vught LA, Boer AMT, Dujardin RWG, Habel M, Xu Z, Brouwer MC, van de Beek D, de Bruin S; Amsterdam UMC COVID-19 Biobank Investigators. Lim EHT, et al. Respir Res. 2022 Dec 24;23(1):375. doi: 10.1186/s12931-022-02278-1. Respir Res. 2022. PMID: 36566174 Free PMC article. Clinical Trial.
ImmunoSep (Personalised Immunotherapy in Sepsis) international double-blind, double-dummy, placebo-controlled randomised clinical trial: study protocol.
Kotsaki A, Pickkers P, Bauer M, Calandra T, Lupse M, Wiersinga WJ, Meylan S, Bloos F, van der Poll T, Slim MA, van Mourik N, Müller MCA, van Vught L, Vlaar APJ, de Nooijer A, Bakkerus L, Weis S, Antonakos N, Netea MG, Giamarellos-Bourboulis EJ. Kotsaki A, et al. Among authors: van mourik n, van der poll t, van vught l. BMJ Open. 2022 Dec 20;12(12):e067251. doi: 10.1136/bmjopen-2022-067251. BMJ Open. 2022. PMID: 36600424 Free PMC article.
Artificial Intelligence for Early Sepsis Detection: A Word of Caution.
Schinkel M, van der Poll T, Wiersinga WJ. Schinkel M, et al. Among authors: van der poll t. Am J Respir Crit Care Med. 2023 Apr 1;207(7):853-854. doi: 10.1164/rccm.202212-2284VP. Am J Respir Crit Care Med. 2023. PMID: 36724366 Free PMC article. No abstract available.
Embracing complexity in sepsis.
Schuurman AR, Sloot PMA, Wiersinga WJ, van der Poll T. Schuurman AR, et al. Among authors: van der poll t. Crit Care. 2023 Mar 11;27(1):102. doi: 10.1186/s13054-023-04374-0. Crit Care. 2023. PMID: 36906606 Free PMC article. Review.
Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19.
Matuozzo D, Talouarn E, Marchal A, Zhang P, Manry J, Seeleuthner Y, Zhang Y, Bolze A, Chaldebas M, Milisavljevic B, Gervais A, Bastard P, Asano T, Bizien L, Barzaghi F, Abolhassani H, Abou Tayoun A, Aiuti A, Alavi Darazam I, Allende LM, Alonso-Arias R, Arias AA, Aytekin G, Bergman P, Bondesan S, Bryceson YT, Bustos IG, Cabrera-Marante O, Carcel S, Carrera P, Casari G, Chaïbi K, Colobran R, Condino-Neto A, Covill LE, Delmonte OM, El Zein L, Flores C, Gregersen PK, Gut M, Haerynck F, Halwani R, Hancerli S, Hammarström L, Hatipoğlu N, Karbuz A, Keles S, Kyheng C, Leon-Lopez R, Franco JL, Mansouri D, Martinez-Picado J, Metin Akcan O, Migeotte I, Morange PE, Morelle G, Martin-Nalda A, Novelli G, Novelli A, Ozcelik T, Palabiyik F, Pan-Hammarström Q, de Diego RP, Planas-Serra L, Pleguezuelo DE, Prando C, Pujol A, Reyes LF, Rivière JG, Rodriguez-Gallego C, Rojas J, Rovere-Querini P, Schlüter A, Shahrooei M, Sobh A, Soler-Palacin P, Tandjaoui-Lambiotte Y, Tipu I, Tresoldi C, Troya J, van de Beek D, Zatz M, Zawadzki P, Al-Muhsen SZ, Alosaimi MF, Alsohime FM, Baris-Feldman H, Butte MJ, Constantinescu SN, Cooper MA, Dalgard CL, Fellay J, Heath JR, Lau YL, Lifton RP, Maniatis T, Mogensen TH, v… See abstract for full author list ➔ Matuozzo D, et al. Genome Med. 2023 Apr 5;15(1):22. doi: 10.1186/s13073-023-01173-8. Genome Med. 2023. PMID: 37020259 Free PMC article.
Age-related changes in plasma biomarkers and their association with mortality in COVID-19.
Michels EHA, Appelman B, de Brabander J, van Amstel RBE, Chouchane O, van Linge CCA, Schuurman AR, Reijnders TDY, Sulzer TAL, Klarenbeek AM, Douma RA; Amsterdam UMC COVID-19 Biobank Study Group; Bos LDJ, Wiersinga WJ, Peters-Sengers H, van der Poll T; Amsterdam UMC COVID-19 Biobank Study Group; van Agtmael M, Algera AG, Appelman B, van Baarle F, Beudel M, Bogaard HJ, Bomers M, Bonta P, Bos L, Botta M, de Brabander J, de Bree G, de Bruin S, Bugiani M, Bulle E, Buis DTP, Chouchane O, Cloherty A, Dijkstra M, Dongelmans DA, Dujardin RWG, Elbers P, Fleuren L, Geerlings S, Geijtenbeek T, Girbes A, Goorhuis B, Grobusch MP, Hagens L, Hamann J, Harris V, Hemke R, Hermans SM, Heunks L, Hollmann M, Horn J, Hovius JW, de Jong HK, de Jong MD, Koning R, Lemkes B, Lim EHT, van Mourik N, Nellen J, Nossent EJ, Olie S, Paulus F, Peters E, Pina-Fuentes DAI, van der Poll T, Preckel B, Prins JM, Raasveld J, Reijnders T, de Rotte MCFJ, Schinkel M, Schultz MJ, Schrauwen FAP, Schuurman A, Schuurmans J, Sigaloff K, Slim MA, Smeele P, Smit M, Stijnis CS, Stilma W, Teunissen C, Thoral P, Tsonas AM, Tuinman PR, van der Valk M, Veelo DP, Volleman C, de V… See abstract for full author list ➔ Michels EHA, et al. Among authors: van agtmael m, van linge cca, van mourik n, van de beek d, van vugt m, van der poll t, van baarle f, van der valk m, van amstel rbe. Eur Respir J. 2023 Jul 7;62(1):2300011. doi: 10.1183/13993003.00011-2023. Print 2023 Jul. Eur Respir J. 2023. PMID: 37080568 Free PMC article.
1,071 results