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Ultraviolet A light induces DNA damage and estrogen-DNA adducts in Fuchs endothelial corneal dystrophy causing females to be more affected.
Liu C, Miyajima T, Melangath G, Miyai T, Vasanth S, Deshpande N, Kumar V, Ong Tone S, Gupta R, Zhu S, Vojnovic D, Chen Y, Rogan EG, Mondal B, Zahid M, Jurkunas UV. Liu C, et al. Among authors: kumar v. Proc Natl Acad Sci U S A. 2020 Jan 7;117(1):573-583. doi: 10.1073/pnas.1912546116. Epub 2019 Dec 18. Proc Natl Acad Sci U S A. 2020. PMID: 31852820 Free PMC article.
Loss of NQO1 generates genotoxic estrogen-DNA adducts in Fuchs Endothelial Corneal Dystrophy.
Miyajima T, Melangath G, Zhu S, Deshpande N, Vasanth S, Mondal B, Kumar V, Chen Y, Price MO, Price FW Jr, Rogan EG, Zahid M, Jurkunas UV. Miyajima T, et al. Among authors: kumar v. Free Radic Biol Med. 2020 Feb 1;147:69-79. doi: 10.1016/j.freeradbiomed.2019.12.014. Epub 2019 Dec 17. Free Radic Biol Med. 2020. PMID: 31857234 Free PMC article.
Eye is the Window to the Brain Pathology.
Kumar V. Kumar V. Curr Adv Ophthalmol. 2018 Aug;1(1):3-4. doi: 10.29199/2638-9940/CAOP-101013. Epub 2017 Nov 15. Curr Adv Ophthalmol. 2018. PMID: 31123726 Free PMC article. No abstract available.
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