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A long-acting LEAP2 analog reduces hepatic steatosis and inflammation and causes marked weight loss in mice.
Shankar K, Metzger NP, Lawrence C, Gupta D, Osborne-Lawrence S, Varshney S, Singh O, Richard CP, Zaykov AN, Rolfts R, DuBois BN, Perez-Tilve D, Mani BK, Hammer STG, Zigman JM. Shankar K, et al. Among authors: richard cp. Mol Metab. 2024 Jun;84:101950. doi: 10.1016/j.molmet.2024.101950. Epub 2024 Apr 30. Mol Metab. 2024. PMID: 38697291 Free PMC article.
Ghrelin deletion and conditional ghrelin cell ablation increase pancreatic islet size in mice.
Gupta D, Burstein AW, Schwalbe DC, Shankar K, Varshney S, Singh O, Paul S, Ogden SB, Osborne-Lawrence S, Metzger NP, Richard CP, Campbell JN, Zigman JM. Gupta D, et al. Among authors: richard cp. J Clin Invest. 2024 May 15;134(10):e182168. doi: 10.1172/JCI182168. J Clin Invest. 2024. PMID: 38747294 Free PMC article. No abstract available.
11 results