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Page 1
Rational design of a SOCS1-edited tumor-infiltrating lymphocyte therapy using CRISPR/Cas9 screens.
Schlabach MR, Lin S, Collester ZR, Wrocklage C, Shenker S, Calnan C, Xu T, Gannon HS, Williams LJ, Thompson F, Dunbar PR, LaMothe RA, Garrett TE, Colletti N, Hohmann AF, Tubo NJ, Bullock CP, Le Mercier I, Sofjan K, Merkin JJ, Keegan S, Kryukov GV, Dugopolski C, Stegmeier F, Wong K, Sharp FA, Cadzow L, Benson MJ. Schlabach MR, et al. Among authors: lamothe ra. J Clin Invest. 2023 Dec 15;133(24):e163096. doi: 10.1172/JCI163096. J Clin Invest. 2023. PMID: 38099496 Free PMC article.
Tolerogenic Nanoparticles Induce Antigen-Specific Regulatory T Cells and Provide Therapeutic Efficacy and Transferrable Tolerance against Experimental Autoimmune Encephalomyelitis.
LaMothe RA, Kolte PN, Vo T, Ferrari JD, Gelsinger TC, Wong J, Chan VT, Ahmed S, Srinivasan A, Deitemeyer P, Maldonado RA, Kishimoto TK. LaMothe RA, et al. Front Immunol. 2018 Mar 2;9:281. doi: 10.3389/fimmu.2018.00281. eCollection 2018. Front Immunol. 2018. PMID: 29552007 Free PMC article.
Improving the efficacy and safety of biologic drugs with tolerogenic nanoparticles.
Kishimoto TK, Ferrari JD, LaMothe RA, Kolte PN, Griset AP, O'Neil C, Chan V, Browning E, Chalishazar A, Kuhlman W, Fu FN, Viseux N, Altreuter DH, Johnston L, Maldonado RA. Kishimoto TK, et al. Among authors: lamothe ra. Nat Nanotechnol. 2016 Oct;11(10):890-899. doi: 10.1038/nnano.2016.135. Epub 2016 Aug 1. Nat Nanotechnol. 2016. PMID: 27479756
Polymeric synthetic nanoparticles for the induction of antigen-specific immunological tolerance.
Maldonado RA, LaMothe RA, Ferrari JD, Zhang AH, Rossi RJ, Kolte PN, Griset AP, O'Neil C, Altreuter DH, Browning E, Johnston L, Farokhzad OC, Langer R, Scott DW, von Andrian UH, Kishimoto TK. Maldonado RA, et al. Among authors: lamothe ra. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):E156-65. doi: 10.1073/pnas.1408686111. Epub 2014 Dec 29. Proc Natl Acad Sci U S A. 2015. PMID: 25548186 Free PMC article.