Wang J - Search Results

1

Structure-Activity Relationship of FL118 Platform Position 7 Versus Position 9-Derived Compounds and Their Mechanism of Action and Antitumor Activity.

Wang W, Ling X, Wang R, Xiong H, Hu L, Yang Z, Wang H, Zhang Y, Wu W, Singh PK, Wang J, Li F, Li Q. Wang W, et al. Among authors: wang h, wang j, wang r. J Med Chem. 2023 Dec 28;66(24):16888-16916. doi: 10.1021/acs.jmedchem.3c01589. Epub 2023 Dec 15. J Med Chem. 2023. PMID: 38100041 Free PMC article.

2

Design, Synthesis, and Evaluation of a Series of Novel Super Long-Acting DPP-4 Inhibitors for the Treatment of Type 2 Diabetes.

Zhang C, Ye F, Wang J, He P, Lei M, Huang L, Huang A, Tang P, Lin H, Liao Y, Liang Y, Ni J, Yan P. Zhang C, et al. Among authors: wang j. J Med Chem. 2020 Jul 9;63(13):7108-7126. doi: 10.1021/acs.jmedchem.0c00374. Epub 2020 Jun 12. J Med Chem. 2020. PMID: 32452679

3

Design, Synthesis, and Evaluation of a Series of Novel Benzocyclobutene Derivatives as General Anesthetics.

Zhang C, Li F, Yu Y, Huang A, He P, Lei M, Wang J, Huang L, Liu Z, Liu J, Wei Y. Zhang C, et al. Among authors: wang j. J Med Chem. 2017 May 11;60(9):3618-3625. doi: 10.1021/acs.jmedchem.7b00253. Epub 2017 Apr 28. J Med Chem. 2017. PMID: 28430431

4

Design, synthesis and evaluation of the novel chalcone derivatives with 2,2-dimethylbenzopyran as HIF-1 inhibitors that possess anti-angiogenic potential.

Xu H, Wang J, Chen Y, Du Y, Chen L, Wu C, Wang L, Chen G. Xu H, et al. Among authors: wang l, wang j. Eur J Med Chem. 2023 Mar 15;250:115171. doi: 10.1016/j.ejmech.2023.115171. Epub 2023 Feb 8. Eur J Med Chem. 2023. PMID: 36774697

5

Discovery of S-phase arresting agents derived from noscapine.

Anderson JT, Ting AE, Boozer S, Brunden KR, Danzig J, Dent T, Harrington JJ, Murphy SM, Perry R, Raber A, Rundlett SE, Wang J, Wang N, Bennani YL. Anderson JT, et al. Among authors: wang j, wang n. J Med Chem. 2005 Apr 21;48(8):2756-8. doi: 10.1021/jm0494220. J Med Chem. 2005. PMID: 15828811

6

Identification of novel and improved antimitotic agents derived from noscapine.

Anderson JT, Ting AE, Boozer S, Brunden KR, Crumrine C, Danzig J, Dent T, Faga L, Harrington JJ, Hodnick WF, Murphy SM, Pawlowski G, Perry R, Raber A, Rundlett SE, Stricker-Krongrad A, Wang J, Bennani YL. Anderson JT, et al. Among authors: wang j. J Med Chem. 2005 Nov 17;48(23):7096-8. doi: 10.1021/jm050674q. J Med Chem. 2005. PMID: 16279766

7

Investigation of 4-piperidinols as novel H3 antagonists.

Anderson JT, Campbell M, Wang J, Brunden KR, Harrington JJ, Stricker-Krongrad A, Song J, Doucette C, Murphy S, Bennani YL. Anderson JT, et al. Among authors: wang j. Bioorg Med Chem Lett. 2010 Nov 1;20(21):6246-9. doi: 10.1016/j.bmcl.2010.08.099. Epub 2010 Aug 24. Bioorg Med Chem Lett. 2010. PMID: 20833043

8

SAR and factor IXa crystal structure of a dual inhibitor of factors IXa and Xa.

Smallheer JM, Alexander RS, Wang J, Wang S, Nakajima S, Rossi KA, Smallwood A, Barbera F, Burdick D, Luettgen JM, Knabb RM, Wexler RR, Jadhav PK. Smallheer JM, et al. Among authors: wang j, wang s. Bioorg Med Chem Lett. 2004 Nov 1;14(21):5263-7. doi: 10.1016/j.bmcl.2004.08.034. Bioorg Med Chem Lett. 2004. PMID: 15454208

9

The identification and optimization of a N-hydroxy urea series of flap endonuclease 1 inhibitors.

Tumey LN, Bom D, Huck B, Gleason E, Wang J, Silver D, Brunden K, Boozer S, Rundlett S, Sherf B, Murphy S, Dent T, Leventhal C, Bailey A, Harrington J, Bennani YL. Tumey LN, et al. Among authors: wang j. Bioorg Med Chem Lett. 2005 Jan 17;15(2):277-81. doi: 10.1016/j.bmcl.2004.10.086. Bioorg Med Chem Lett. 2005. PMID: 15603939

10

alpha-(2-Pyridine)benzyl aryl ketones as potential hypocholesteremic agents.

Hewitt LE, Wade DR, Sinsheimer JE, Wang JH, Drach JC, Burckhalter JH. Hewitt LE, et al. Among authors: wang jh. J Med Chem. 1978 Dec;21(12):1339-40. doi: 10.1021/jm00210a038. J Med Chem. 1978. PMID: 722749

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