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Page 1
Sigma receptor and aquaporin modulators: chiral resolution, configurational assignment, and preliminary biological profile of RC752 enantiomers.
Listro R, Marra A, Cavalloro V, Rossino G, Linciano P, Rossi D, Casali E, De Amici M, Mazzeo G, Longhi G, Fusè M, Dondio G, Pellavio G, Laforenza U, Schepmann D, Wünsch B, Collina S. Listro R, et al. Among authors: dondio g. J Pharm Biomed Anal. 2024 Feb 15;239:115902. doi: 10.1016/j.jpba.2023.115902. Epub 2023 Dec 14. J Pharm Biomed Anal. 2024. PMID: 38101238 Free article.
Discovery of RC-752, a Novel Sigma-1 Receptor Antagonist with Antinociceptive Activity: A Promising Tool for Fighting Neuropathic Pain.
Rossino G, Marra A, Listro R, Peviani M, Poggio E, Curti D, Pellavio G, Laforenza U, Dondio G, Schepmann D, Wünsch B, Bedeschi M, Marino N, Tesei A, Ha HJ, Kim YH, Ann J, Lee J, Linciano P, Di Giacomo M, Rossi D, Collina S. Rossino G, et al. Among authors: dondio g. Pharmaceuticals (Basel). 2023 Jul 5;16(7):962. doi: 10.3390/ph16070962. Pharmaceuticals (Basel). 2023. PMID: 37513874 Free PMC article.
Novel multitarget directed ligands inspired by riluzole: A serendipitous synthesis of substituted benzo[b][1,4]thiazepines potentially useful as neuroprotective agents.
Maramai S, Saletti M, Paolino M, Giuliani G, Cazzola J, Spaiardi P, Talpo F, Frosini M, Pifferi A, Ballarotto M, Carotti A, Poggialini F, Vagaggini C, Dreassi E, Giorgi G, Dondio G, Cappelli A, Rosario Biella G, Anzini M. Maramai S, et al. Among authors: dondio g. Bioorg Med Chem. 2024 Oct 1;112:117872. doi: 10.1016/j.bmc.2024.117872. Epub 2024 Aug 13. Bioorg Med Chem. 2024. PMID: 39153378
Development of N-(4-(1H-Imidazol-1-yl)phenyl)-4-chlorobenzenesulfonamide, a Novel Potent Inhibitor of β-Catenin with Enhanced Antitumor Activity and Metabolic Stability.
Puxeddu M, Ling L, Ripa S, D'Ambrosio M, Nalli M, Parisi A, Sciò P, Coluccia A, Granese A, Santelli M, Masci D, Cuřínová P, Naro C, Sette C, Pastore A, Stornaiuolo M, Bigogno C, Dondio G, Di Magno L, Canettieri G, Liu T, Silvestri R, La Regina G. Puxeddu M, et al. Among authors: dondio g. J Med Chem. 2024 Nov 28;67(22):20298-20314. doi: 10.1021/acs.jmedchem.4c01708. Epub 2024 Nov 7. J Med Chem. 2024. PMID: 39508273
SAR Analysis of Novel Coxsackie virus A9 Capsid Binders.
Tammaro C, Plavec Z, Myllymäki L, Mitchell C, Consalvi S, Biava M, Ciogli A, Domanska A, Leppilampi V, Buckner C, Manetto S, Sciò P, Coluccia A, Laajala M, Dondio GM, Bigogno C, Marjomäki V, Butcher SJ, Poce G. Tammaro C, et al. Among authors: dondio gm. J Med Chem. 2024 Oct 10;67(19):17144-17161. doi: 10.1021/acs.jmedchem.4c00701. Epub 2024 Sep 18. J Med Chem. 2024. PMID: 39292620
4-(3-Phenylsulfonylindol-2-yl)-1-(pyridin-2-yl)piperazinyl-methanones as Potent Inhibitors of both SARS-CoV-2 and HCoV-OC43 Viruses.
Puxeddu M, Donalisio M, Bugert JJ, Corona A, Cocomazzi P, Milani M, Hucke F, Arduino I, Esposito F, Moretti P, Ortore MG, Nalli M, Manetto S, Mazzoccanti G, Bigogno C, Dondio G, Sciò P, Coluccia A, Fracella M, Antonelli G, Lembo D, Tramontano E, Silvestri R, Mastrangelo E, La Regina G. Puxeddu M, et al. Among authors: dondio g. ACS Infect Dis. 2024 Sep 13;10(9):3158-3175. doi: 10.1021/acsinfecdis.4c00108. Epub 2024 Aug 3. ACS Infect Dis. 2024. PMID: 39096289
Novel N-(Heterocyclylphenyl)benzensulfonamide Sharing an Unreported Binding Site with T-Cell Factor 4 at the β-Catenin Armadillo Repeats Domain as an Anticancer Agent.
Nalli M, Di Magno L, Wen Y, Liu X, D'Ambrosio M, Puxeddu M, Parisi A, Sebastiani J, Sorato A, Coluccia A, Ripa S, Di Pastena F, Capelli D, Montanari R, Masci D, Urbani A, Naro C, Sette C, Orlando V, D'Angelo S, Biagioni S, Bigogno C, Dondio G, Pastore A, Stornaiuolo M, Canettieri G, Liu T, Silvestri R, La Regina G. Nalli M, et al. Among authors: dondio g. ACS Pharmacol Transl Sci. 2023 Jul 3;6(7):1087-1103. doi: 10.1021/acsptsci.3c00092. eCollection 2023 Jul 14. ACS Pharmacol Transl Sci. 2023. PMID: 37470018 Free PMC article.
Favorable Preclinical Pharmacological Profile of a Novel Antimalarial Pyrrolizidinylmethyl Derivative of 4-amino-7-chloroquinoline with Potent In Vitro and In Vivo Activities.
Basilico N, Parapini S, D'Alessandro S, Misiano P, Romeo S, Dondio G, Yardley V, Vivas L, Nasser S, Rénia L, Russell BM, Suwanarusk R, Nosten F, Sparatore A, Taramelli D. Basilico N, et al. Among authors: dondio g. Biomolecules. 2023 May 14;13(5):836. doi: 10.3390/biom13050836. Biomolecules. 2023. PMID: 37238706 Free PMC article.
52 results