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Addressing the Biochemical Foundations of a Glucose-Based "Trojan Horse"-Strategy to Boron Neutron Capture Therapy: From Chemical Synthesis to In Vitro Assessment.
Matović J, Järvinen J, Bland HC, Sokka IK, Imlimthan S, Ferrando RM, Huttunen KM, Timonen J, Peräniemi S, Aitio O, Airaksinen AJ, Sarparanta M, Johansson MP, Rautio J, Ekholm FS. Matović J, et al. Among authors: jarvinen j. Mol Pharm. 2020 Oct 5;17(10):3885-3899. doi: 10.1021/acs.molpharmaceut.0c00630. Epub 2020 Sep 2. Mol Pharm. 2020. PMID: 32787269 Free PMC article.
L-Type Amino Acid Transporter 1 Enables the Efficient Brain Delivery of Small-Sized Prodrug across the Blood-Brain Barrier and into Human and Mouse Brain Parenchymal Cells.
Montaser AB, Järvinen J, Löffler S, Huttunen J, Auriola S, Lehtonen M, Jalkanen A, Huttunen KM. Montaser AB, et al. Among authors: jarvinen j. ACS Chem Neurosci. 2020 Dec 16;11(24):4301-4315. doi: 10.1021/acschemneuro.0c00564. Epub 2020 Nov 23. ACS Chem Neurosci. 2020. PMID: 33228353
Exploring the Biochemical Foundations of a Successful GLUT1-Targeting Strategy to BNCT: Chemical Synthesis and In Vitro Evaluation of the Entire Positional Isomer Library of ortho-Carboranylmethyl-Bearing Glucoconjugates.
Matović J, Järvinen J, Sokka IK, Imlimthan S, Raitanen JE, Montaser A, Maaheimo H, Huttunen KM, Peräniemi S, Airaksinen AJ, Sarparanta M, Johansson MP, Rautio J, Ekholm FS. Matović J, et al. Among authors: jarvinen j. Mol Pharm. 2021 Jan 4;18(1):285-304. doi: 10.1021/acs.molpharmaceut.0c00917. Epub 2020 Dec 1. Mol Pharm. 2021. PMID: 33390018
Altering distribution profile of palbociclib by its prodrugs.
Järvinen J, Montaser AB, Adla SK, Leppänen J, Lehtonen M, Vellonen KS, Laitinen T, Jalkanen A, Elmquist WF, Timonen J, Huttunen KM, Rautio J. Järvinen J, et al. Eur J Pharm Sci. 2024 Jan 1;192:106637. doi: 10.1016/j.ejps.2023.106637. Epub 2023 Nov 13. Eur J Pharm Sci. 2024. PMID: 37967656 Free article.
Asymmetric Synthesis and Biological Evaluation of Both Enantiomers of 5- and 6-Boronotryptophan as Potential Boron Delivery Agents for Boron Neutron Capture Therapy.
Retini M, Järvinen J, Bahrami K, Tampio J, Bartoccini F, Riihelä P, Pehkonen H, Värä A, Laitinen T, Huttunen KM, Rautio J, Piersanti G, Timonen JM. Retini M, et al. Among authors: jarvinen j. ACS Med Chem Lett. 2024 Nov 11;15(12):2121-2128. doi: 10.1021/acsmedchemlett.4c00241. eCollection 2024 Dec 12. ACS Med Chem Lett. 2024. PMID: 39691535 Free PMC article.
92 results