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108 results

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Page 1
Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1.
Coleman DJL, Keane P, Chin PS, Ames L, Kellaway S, Blair H, Khan N, Griffin J, Holmes E, Maytum A, Potluri S, Strate L, Koscielniak K, Raghavan M, Bushweller J, Heidenreich O, Rabbitts T, Cockerill PN, Bonifer C. Coleman DJL, et al. Among authors: bushweller j. iScience. 2024 Mar 26;27(4):109576. doi: 10.1016/j.isci.2024.109576. eCollection 2024 Apr 19. iScience. 2024. PMID: 38638836 Free PMC article.
N-MYC regulates cell survival via eIF4G1 in inv(16) acute myeloid leukemia.
Peramangalam PS, Surapally S, Veltri AJ, Zheng S, Burns R, Zhu N, Rao S, Muller-Tidow C, Bushweller JH, Pulikkan JA. Peramangalam PS, et al. Among authors: bushweller jh. Sci Adv. 2024 Mar;10(9):eadh8493. doi: 10.1126/sciadv.adh8493. Epub 2024 Feb 28. Sci Adv. 2024. PMID: 38416825 Free PMC article.
Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth.
Coleman DJL, Keane P, Luque-Martin R, Chin PS, Blair H, Ames L, Kellaway SG, Griffin J, Holmes E, Potluri S, Assi SA, Bushweller J, Heidenreich O, Cockerill PN, Bonifer C. Coleman DJL, et al. Among authors: bushweller j. Cell Rep. 2023 Dec 26;42(12):113568. doi: 10.1016/j.celrep.2023.113568. Epub 2023 Dec 15. Cell Rep. 2023. PMID: 38104314 Free PMC article.
Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth.
Coleman DJL, Keane P, Luque-Martin R, Chin PS, Blair H, Ames L, Kellaway SG, Griffin J, Holmes E, Potluri S, Assi SA, Bushweller J, Heidenreich O, Cockerill PN, Bonifer C. Coleman DJL, et al. Among authors: bushweller j. bioRxiv [Preprint]. 2023 Jul 19:2023.07.18.549495. doi: 10.1101/2023.07.18.549495. bioRxiv. 2023. Update in: Cell Rep. 2023 Dec 26;42(12):113568. doi: 10.1016/j.celrep.2023.113568 PMID: 37503022 Free PMC article. Updated. Preprint.
An erythroid-to-myeloid cell fate conversion is elicited by LSD1 inactivation.
Yu L, Myers G, Ku CJ, Schneider E, Wang Y, Singh SA, Jearawiriyapaisarn N, White A, Moriguchi T, Khoriaty R, Yamamoto M, Rosenfeld MG, Pedron J, Bushweller JH, Lim KC, Engel JD. Yu L, et al. Among authors: bushweller jh. Blood. 2021 Nov 4;138(18):1691-1704. doi: 10.1182/blood.2021011682. Blood. 2021. PMID: 34324630 Free PMC article.
108 results