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Mutual Amplification of GLI2/Hedgehog and Transcription Factor JUN/AP-1 Signaling in Fibroblasts in Systemic Sclerosis: Potential Implications for Combined Therapies.
Bergmann C, Chenguiti Fakhouri S, Trinh-Minh T, Filla T, Rius Rigau A, Ekici AB, Merlevede B, Hallenberger L, Zhu H, Dees C, Matei AE, Auth J, Györfi AH, Zhou X, Rauber S, Bozec A, Dickel N, Liang C, Kunz M, Schett G, Distler JHW. Bergmann C, et al. Among authors: trinh minh t. Arthritis Rheumatol. 2025 Jan;77(1):92-98. doi: 10.1002/art.42979. Epub 2024 Oct 20. Arthritis Rheumatol. 2025. PMID: 39187464 Free PMC article.
Noncanonical WNT5A controls the activation of latent TGF-β to drive fibroblast activation and tissue fibrosis.
Trinh-Minh T, Chen CW, Tran Manh C, Li YN, Zhu H, Zhou X, Chakraborty D, Zhang Y, Rauber S, Dees C, Lin NY, Kah D, Gerum R, Bergmann C, Kreuter A, Reuter C, Groeber-Becker F, Eckes B, Distler O, Fabry B, Ramming A, Schambony A, Schett G, Distler JH. Trinh-Minh T, et al. J Clin Invest. 2024 Mar 26;134(10):e159884. doi: 10.1172/JCI159884. J Clin Invest. 2024. PMID: 38747285 Free PMC article.
Combined inhibition of IL-1, IL-33 and IL-36 signalling by targeting IL1RAP ameliorates skin and lung fibrosis in preclinical models of systemic sclerosis.
Grönberg C, Rattik S, Tran-Manh C, Zhou X, Rius Rigau A, Li YN, Györfi AH, Dickel N, Kunz M, Kreuter A, Matei EA, Zhu H, Skoog P, Liberg D, Distler JH, Trinh-Minh T. Grönberg C, et al. Among authors: trinh minh t. Ann Rheum Dis. 2024 Aug 27;83(9):1156-1168. doi: 10.1136/ard-2023-225158. Ann Rheum Dis. 2024. PMID: 38594058 Free PMC article.
Attenuation of fibroblast activation and fibrosis by adropin in systemic sclerosis.
Liang M, Dickel N, Györfi AH, SafakTümerdem B, Li YN, Rigau AR, Liang C, Hong X, Shen L, Matei AE, Trinh-Minh T, Tran-Manh C, Zhou X, Zehender A, Kreuter A, Zou H, Schett G, Kunz M, Distler JHW. Liang M, et al. Among authors: trinh minh t. Sci Transl Med. 2024 Mar 27;16(740):eadd6570. doi: 10.1126/scitranslmed.add6570. Epub 2024 Mar 27. Sci Transl Med. 2024. PMID: 38536934
Effect of Anti-S100A4 Monoclonal Antibody Treatment on Experimental Skin Fibrosis and Systemic Sclerosis-Specific Transcriptional Signatures in Human Skin.
Trinh-Minh T, Györfi AH, Tomcik M, Tran-Manh C, Zhou X, Dickel N, Tümerdem BS, Kreuter A, Burmann SN, Borchert SV, Hussain RI, Hallén J, Klingelhöfer J, Kunz M, Distler JHW. Trinh-Minh T, et al. Arthritis Rheumatol. 2024 May;76(5):783-795. doi: 10.1002/art.42781. Epub 2024 Feb 15. Arthritis Rheumatol. 2024. PMID: 38108109
S100A4-neutralizing monoclonal antibody 6B12 counteracts the established experimental skin fibrosis induced by bleomycin.
Švec X, Štorkánová H, Trinh-Minh T, Tran MC, Štorkánová L, Hulejová H, Oreská S, Heřmánková B, Bečvář R, Pavelka K, Vencovský J, Klingelhöfer J, Hussain RI, Hallén J, Šenolt L, Distler JHW, Tomčík M. Švec X, et al. Among authors: trinh minh t. Rheumatology (Oxford). 2024 Mar 1;63(3):817-825. doi: 10.1093/rheumatology/kead295. Rheumatology (Oxford). 2024. PMID: 37314987 Free PMC article.
22 results