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Identification of unstable regulatory and autoreactive effector T cells that are expanded in patients with FOXP3 mutations.
Borna Š, Lee E, Nideffer J, Ramachandran A, Wang B, Baker J, Mavers M, Lakshmanan U, Narula M, Garrett AK, Schulze J, Olek S, Marois L, Gernez Y, Bhatia M, Chong HJ, Walter J, Kitcharoensakkul M, Lang A, Cooper MA, Bertaina A, Roncarolo MG, Meffre E, Bacchetta R. Borna Š, et al. Among authors: lee e. Sci Transl Med. 2023 Dec 20;15(727):eadg6822. doi: 10.1126/scitranslmed.adg6822. Epub 2023 Dec 20. Sci Transl Med. 2023. PMID: 38117899 Free PMC article.
CRISPR-based gene editing enables FOXP3 gene repair in IPEX patient cells.
Goodwin M, Lee E, Lakshmanan U, Shipp S, Froessl L, Barzaghi F, Passerini L, Narula M, Sheikali A, Lee CM, Bao G, Bauer CS, Miller HK, Garcia-Lloret M, Butte MJ, Bertaina A, Shah A, Pavel-Dinu M, Hendel A, Porteus M, Roncarolo MG, Bacchetta R. Goodwin M, et al. Among authors: lee e, lee cm. Sci Adv. 2020 May 6;6(19):eaaz0571. doi: 10.1126/sciadv.aaz0571. eCollection 2020 May. Sci Adv. 2020. PMID: 32494707 Free PMC article.
Towards gene therapy for IPEX syndrome.
Borna S, Lee E, Sato Y, Bacchetta R. Borna S, et al. Among authors: lee e. Eur J Immunol. 2022 May;52(5):705-716. doi: 10.1002/eji.202149210. Epub 2022 Apr 13. Eur J Immunol. 2022. PMID: 35355253 Free PMC article. Review.
Multi-modal analysis reveals tumor and immune features distinguishing EBV-positive and EBV-negative post-transplant lymphoproliferative disorders.
Toh J, Reitsma AJ, Tajima T, Younes SF, Ezeiruaku C, Jenkins KC, Peña JK, Zhao S, Wang X, Lee EYZ, Glass MC, Kalesinskas L, Ganesan A, Liang I, Pai JA, Harden JT, Vallania F, Vizcarra EA, Bhagat G, Craig FE, Swerdlow SH, Morscio J, Dierickx D, Tousseyn T, Satpathy AT, Krams SM, Natkunam Y, Khatri P, Martinez OM. Toh J, et al. Among authors: lee eyz. Cell Rep Med. 2024 Dec 17;5(12):101851. doi: 10.1016/j.xcrm.2024.101851. Epub 2024 Dec 9. Cell Rep Med. 2024. PMID: 39657667 Free article.
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