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FDA Approval Summary: Olaparib in Combination With Abiraterone for Treatment of Patients With BRCA-Mutated Metastatic Castration-Resistant Prostate Cancer.
Fallah J, Xu J, Weinstock C, Brave MH, Bloomquist E, Fiero MH, Schaefer T, Pathak A, Abukhdeir A, Bhatnagar V, Chiu HJ, Ricks T, John C, Hamed S, Lee C, Pierce WF, Kalavar S, Philip R, Tang S, Amiri-Kordestani L, Pazdur R, Kluetz PG, Suzman D. Fallah J, et al. Among authors: schaefer t. J Clin Oncol. 2024 Feb 10;42(5):605-613. doi: 10.1200/JCO.23.01868. Epub 2023 Dec 21. J Clin Oncol. 2024. PMID: 38127780 Clinical Trial.
US Food and Drug Administration Approval Summary: Capivasertib With Fulvestrant for Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Locally Advanced or Metastatic Breast Cancer With PIK3CA/AKT1/PTEN Alterations.
Dilawari A, Buturla J, Osgood C, Gao X, Chen W, Ricks TK, Schaefer T, Avasarala S, Reyes Turcu F, Pathak A, Kalavar S, Bhatnagar V, Collazo J, Rahman NA, Mixter B, Tang S, Pazdur R, Kluetz P, Amiri-Kordestani L. Dilawari A, et al. Among authors: schaefer t. J Clin Oncol. 2024 Dec;42(34):4103-4113. doi: 10.1200/JCO.24.00427. Epub 2024 Aug 19. J Clin Oncol. 2024. PMID: 39159418 Clinical Trial.
Rapid, potent, and persistent covalent chemical probes to deconvolute PI3Kα signaling.
Bissegger L, Constantin TA, Keles E, Raguž L, Barlow-Busch I, Orbegozo C, Schaefer T, Borlandelli V, Bohnacker T, Sriramaratnam R, Schäfer A, Gstaiger M, Burke JE, Borsari C, Wymann MP. Bissegger L, et al. Among authors: schaefer t. Chem Sci. 2024 Nov 12;15(48):20274-20291. doi: 10.1039/d4sc05459h. eCollection 2024 Dec 11. Chem Sci. 2024. PMID: 39568927 Free PMC article.
Patterns of Brain Maturation in Autism and Their Molecular Associations.
Pretzsch CM, Arenella M, Lerch JP, Lombardo MV, Beckmann C, Schaefer T, Leyhausen J, Gurr C, Bletsch A, Berg LM, Seelemeyer H, Floris DL, Oakley B, Loth E, Bourgeron T, Charman T, Buitelaar J, McAlonan G, Murphy D, Ecker C; EU-AIMS LEAP Group. Pretzsch CM, et al. Among authors: schaefer t. JAMA Psychiatry. 2024 Dec 1;81(12):1253-1264. doi: 10.1001/jamapsychiatry.2024.3194. JAMA Psychiatry. 2024. PMID: 39412777 Free PMC article.
Nuclear and cytosolic fractions of SOX2 synergize as transcriptional and translational co-regulators of cell fate.
Schaefer T, Mittal N, Wang H, Ataman M, Candido S, Lötscher J, Velychko S, Tintignac L, Bock T, Börsch A, Baßler J, Rao TN, Zmajkovic J, Roffeis S, Löliger J, Jacob F, Dumlin A, Schürch C, Schmidt A, Skoda RC, Wymann MP, Hess C, Schöler HR, Zaehres H, Hurt E, Zavolan M, Lengerke C. Schaefer T, et al. Cell Rep. 2024 Oct 22;43(10):114807. doi: 10.1016/j.celrep.2024.114807. Epub 2024 Oct 3. Cell Rep. 2024. PMID: 39368083 Free article.
Guidelines for preventing and slowing myopia progression in Brazilian children.
Ejzenbaum F, Schaefer TMC, Cunha C, Rossetto JD, Godinho IF, Nakanami CR, Noma RK, Hopker LM. Ejzenbaum F, et al. Among authors: schaefer tmc. Arq Bras Oftalmol. 2024 Aug 5;87(5):e20230009. doi: 10.5935/0004-2749.2023-0009. eCollection 2024. Arq Bras Oftalmol. 2024. PMID: 39109702 Free PMC article.
327 results