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Mitochondrial citrate carrier SLC25A1 is a dosage-dependent regulator of metabolic reprogramming and morphogenesis in the developing heart.
Ohanele C, Peoples JN, Karlstaedt A, Geiger JT, Gayle AD, Ghazal N, Sohani F, Brown ME, Davis ME, Porter GA, Faundez V, Kwong JQ. Ohanele C, et al. Among authors: faundez v. bioRxiv [Preprint]. 2024 May 13:2023.05.22.541833. doi: 10.1101/2023.05.22.541833. bioRxiv. 2024. Update in: Commun Biol. 2024 Oct 31;7(1):1422. doi: 10.1038/s42003-024-07110-8. PMID: 37292906 Free PMC article. Updated. Preprint.
Cross-species transcriptomic analysis identifies mitochondrial dysregulation as a functional consequence of the schizophrenia-associated 3q29 deletion.
Purcell RH, Sefik E, Werner E, King AT, Mosley TJ, Merritt-Garza ME, Chopra P, McEachin ZT, Karne S, Raj N, Vaglio BJ, Sullivan D, Firestein BL, Tilahun K, Robinette MI, Warren ST, Wen Z, Faundez V, Sloan SA, Bassell GJ, Mulle JG. Purcell RH, et al. Among authors: faundez v. bioRxiv [Preprint]. 2023 May 26:2023.01.27.525748. doi: 10.1101/2023.01.27.525748. bioRxiv. 2023. Update in: Sci Adv. 2023 Aug 18;9(33):eadh0558. doi: 10.1126/sciadv.adh0558. PMID: 36747819 Free PMC article. Updated. Preprint.
Mitochondrial Proteostasis Requires Genes Encoded in a Neurodevelopmental Syndrome Locus.
Gokhale A, Lee CE, Zlatic SA, Freeman AAH, Shearing N, Hartwig C, Ogunbona O, Bassell JL, Wynne ME, Werner E, Xu C, Wen Z, Duong D, Seyfried NT, Bearden CE, Oláh VJ, Rowan MJM, Glausier JR, Lewis DA, Faundez V. Gokhale A, et al. Among authors: faundez v. J Neurosci. 2021 Aug 4;41(31):6596-6616. doi: 10.1523/JNEUROSCI.2197-20.2021. Epub 2021 Jul 14. J Neurosci. 2021. PMID: 34261699 Free PMC article.
Shared mechanisms across the major psychiatric and neurodegenerative diseases.
Wingo TS, Liu Y, Gerasimov ES, Vattathil SM, Wynne ME, Liu J, Lori A, Faundez V, Bennett DA, Seyfried NT, Levey AI, Wingo AP. Wingo TS, et al. Among authors: faundez v. Nat Commun. 2022 Jul 26;13(1):4314. doi: 10.1038/s41467-022-31873-5. Nat Commun. 2022. PMID: 35882878 Free PMC article.
128 results