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Targeting farnesylation as a novel therapeutic approach in HRAS-mutant rhabdomyosarcoma.
Odeniyide P, Yohe ME, Pollard K, Vaseva AV, Calizo A, Zhang L, Rodriguez FJ, Gross JM, Allen AN, Wan X, Somwar R, Schreck KC, Kessler L, Wang J, Pratilas CA. Odeniyide P, et al. Among authors: zhang l. Oncogene. 2022 May;41(21):2973-2983. doi: 10.1038/s41388-022-02305-x. Epub 2022 Apr 22. Oncogene. 2022. PMID: 35459782 Free PMC article.
CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon restoration of RB function in malignant peripheral nerve sheath tumors.
Wang J, Calizo A, Zhang L, Pino JC, Lyu Y, Pollard K, Zhang X, Larsson AT, Conniff E, Llosa N, Wood DK, Largaespada DA, Moody SE, Gosline SJ, Hirbe AC, Pratilas CA. Wang J, et al. Among authors: zhang l, zhang x. bioRxiv [Preprint]. 2023 Feb 3:2023.02.02.526674. doi: 10.1101/2023.02.02.526674. bioRxiv. 2023. Update in: Sci Adv. 2023 Nov 24;9(47):eadg8876. doi: 10.1126/sciadv.adg8876 PMID: 36778419 Free PMC article. Updated. Preprint.
CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon RB function in malignant peripheral nerve sheath tumors.
Wang J, Calizo A, Zhang L, Pino JC, Lyu Y, Pollard K, Zhang X, Larsson AT, Conniff E, Llosa NJ, Wood DK, Largaespada DA, Moody SE, Gosline SJ, Hirbe AC, Pratilas CA. Wang J, et al. Among authors: zhang l, zhang x. Sci Adv. 2023 Nov 24;9(47):eadg8876. doi: 10.1126/sciadv.adg8876. Epub 2023 Nov 24. Sci Adv. 2023. PMID: 38000020 Free PMC article.
Multidimensional Immunotyping of Human NF1-Associated Peripheral Nerve Sheath Tumors Uncovers Tumor-Associated Macrophages as Key Drivers of Immune Evasion in the Tumor Microenvironment.
Zhang L, Maalouf A, Makri SC, Banerjee J, Suru A, Tam AJ, Calizo A, Pollard K, Wang J, Danilova L, Ioannou M, Levin AS, Morris CD, Rhee DS, Belzberg AJ, Blakeley JO, Ladle BH, Pardoll DM, Lucas CG, Rodriguez FJ, Gross JM, Anders RA, Pratilas CA, Llosa NJ. Zhang L, et al. Clin Cancer Res. 2024 Dec 2;30(23):5459-5472. doi: 10.1158/1078-0432.CCR-24-1454. Clin Cancer Res. 2024. PMID: 39321200
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