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Page 1
Cholesterol loss during glutamate-mediated excitotoxicity.
Sodero AO, Vriens J, Ghosh D, Stegner D, Brachet A, Pallotto M, Sassoè-Pognetto M, Brouwers JF, Helms JB, Nieswandt B, Voets T, Dotti CG. Sodero AO, et al. Among authors: stegner d. EMBO J. 2012 Apr 4;31(7):1764-73. doi: 10.1038/emboj.2012.31. Epub 2012 Feb 17. EMBO J. 2012. PMID: 22343944 Free PMC article.
Critical shifts in lipid metabolism promote megakaryocyte differentiation and proplatelet formation.
de Jonckheere B, Kollotzek F, Münzer P, Göb V, Fischer M, Mott K, Coman C, Troppmair NN, Manke MC, Zdanyte M, Harm T, Sigle M, Kopczynski D, Bileck A, Gerner C, Hoffmann N, Heinzmann D, Assinger A, Gawaz M, Stegner D, Schulze H, Borst O, Ahrends R. de Jonckheere B, et al. Among authors: stegner d. Nat Cardiovasc Res. 2023 Sep;2:835-852. doi: 10.1038/s44161-023-00325-8. Epub 2023 Aug 31. Nat Cardiovasc Res. 2023. PMID: 38075556 Free PMC article.
Thrombopoiesis is spatially regulated by the bone marrow vasculature.
Stegner D, vanEeuwijk JMM, Angay O, Gorelashvili MG, Semeniak D, Pinnecker J, Schmithausen P, Meyer I, Friedrich M, Dütting S, Brede C, Beilhack A, Schulze H, Nieswandt B, Heinze KG. Stegner D, et al. Nat Commun. 2017 Jul 25;8(1):127. doi: 10.1038/s41467-017-00201-7. Nat Commun. 2017. PMID: 28743899 Free PMC article.
Evidence that GPVI is Expressed as a Mixture of Monomers and Dimers, and that the D2 Domain is not Essential for GPVI Activation.
Clark JC, Neagoe RAI, Zuidscherwoude M, Kavanagh DM, Slater A, Martin EM, Soave M, Stegner D, Nieswandt B, Poulter NS, Hummert J, Herten DP, Tomlinson MG, Hill SJ, Watson SP. Clark JC, et al. Among authors: stegner d. Thromb Haemost. 2021 Nov;121(11):1435-1447. doi: 10.1055/a-1401-5014. Epub 2021 Apr 14. Thromb Haemost. 2021. PMID: 33638140
Congenital valvular defects associated with deleterious mutations in the PLD1 gene.
Ta-Shma A, Zhang K, Salimova E, Zernecke A, Sieiro-Mosti D, Stegner D, Furtado M, Shaag A, Perles Z, Nieswandt B, Rein AJ, Rosenthal N, Neiman AM, Elpeleg O. Ta-Shma A, et al. Among authors: stegner d. J Med Genet. 2017 Apr;54(4):278-286. doi: 10.1136/jmedgenet-2016-104259. Epub 2016 Oct 31. J Med Genet. 2017. PMID: 27799408
Divalent nanobodies to platelet CLEC-2 can serve as agonists or antagonists.
Clark JC, Martin EM, Morán LA, Di Y, Wang X, Zuidscherwoude M, Brown HC, Kavanagh DM, Hummert J, Eble JA, Nieswandt B, Stegner D, Pollitt AY, Herten DP, Tomlinson MG, García A, Watson SP. Clark JC, et al. Among authors: stegner d. Commun Biol. 2023 Apr 7;6(1):376. doi: 10.1038/s42003-023-04766-6. Commun Biol. 2023. PMID: 37029319 Free PMC article.
Experimental validation of computerised models of clustering of platelet glycoprotein receptors that signal via tandem SH2 domain proteins.
Maqsood Z, Clark JC, Martin EM, Cheung YFH, Morán LA, Watson SET, Pike JA, Di Y, Poulter NS, Slater A, Lange BMH, Nieswandt B, Eble JA, Tomlinson MG, Owen DM, Stegner D, Bridge LJ, Wierling C, Watson SP. Maqsood Z, et al. Among authors: stegner d. PLoS Comput Biol. 2022 Nov 28;18(11):e1010708. doi: 10.1371/journal.pcbi.1010708. eCollection 2022 Nov. PLoS Comput Biol. 2022. PMID: 36441766 Free PMC article.
110 results